Dysphagia in Alzheimer's disease [Dysphagie dans la maladie d'Alzheimer]

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dc.contributor.authorSeçil Y.
dc.contributor.authorArıcı Ş.
dc.contributor.authorİncesu T.K.
dc.contributor.authorGürgör N.
dc.contributor.authorBeckmann Y.
dc.contributor.authorErtekin C.
dc.date.accessioned2019-10-27T08:20:34Z
dc.date.available2019-10-27T08:20:34Z
dc.date.issued2016
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective To investigate electrophysiological parameters of swallowing in all stages of Alzheimer's disease. Methods Forty Alzheimer's disease patients, 20 age-matched normal controls and 20 young normal controls were included. Dysphagia limit (DL) and sequential water swallowing (SWS) tests were performed. Cardiac rhythm, respiration and sympathetic skin responses were concomitantly recorded. Results Dysphagia was found in 30/40 (75%) of Alzheimer's disease patients. Mean volume at the DL test was significantly reduced (16.5 ± 1.0 mL) in the Alzheimer's disease group. Swallowing and apnea times in the SWS test were significantly prolonged in elderly controls, but even longer in Alzheimer's disease patients. Conclusions Alzheimer's disease patients had electrophysiological features of dysphagia, even in the early period of disease. The cortical involvement and severity of cognitive disorder can increase swallowing problems, but subclinical signs of dysphagia may be observed even in patients with mild or moderate Alzheimer's disease. © 2016 Elsevier Masson SASen_US
dc.identifier.doi10.1016/j.neucli.2015.12.007en_US
dc.identifier.endpage178en_US
dc.identifier.issn0987-7053
dc.identifier.issue3en_US
dc.identifier.pmid26924307en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage171en_US
dc.identifier.urihttps://doi.org/10.1016/j.neucli.2015.12.007
dc.identifier.urihttps://hdl.handle.net/11454/25714
dc.identifier.volume46en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Masson SASen_US
dc.relation.ispartofNeurophysiologie Cliniqueen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAlzheimer's diseaseen_US
dc.subjectDeglutitionen_US
dc.subjectDementiaen_US
dc.subjectElectrophysiologyen_US
dc.subjectSwallowingen_US
dc.titleDysphagia in Alzheimer's disease [Dysphagie dans la maladie d'Alzheimer]en_US
dc.typeArticleen_US

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