Ankilozan Spondilite Bağlı Pulmoner Tutulumun Bath indeksleri, Yaşam Kalitesi ve Psikolojik Semptomlar Üzerine Etkisi
Küçük Resim Yok
Tarih
2009
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Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Ankilozan spondilit (AS) hastalarında ağrı, tutukluk nedeniyle bozulan psikolojik durum ve yaşam kalitesi, buna ek olarak eklenen pulmoner tutulumunun ortaya çıkmasıyla daha da çok kötüleşmektedir. Bu açıdan, AS hastalarının pulmoner tutulumunun belirlenmesi önemlidir. Bu çalışmada, AS hastalarında pulmoner tutulumu saptamak ve pulmoner tutulumunun Bath indeksleri, yaşam kalitesi ve psikolojik semptomlar üzerine olan etkisini incelemek amaçlanmıştır.Yöntem ve Gereçler: Yirmialtı AS hastası (ortalama yaş: 47.5±10.8 yıl) çalışmaya alındı. Hastaların pulmoner sisteme ait durumları spirometrik ölçüm ve radyografik yöntemlerle [(akciğer grafisi ile yüksek rezolüsyonlu bilgisayarlı tomografi (YRBT)], klinik durumları Bath indeksleri [Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Spondylitis Metrology Index (BASMI), Bath Ankylosing Spondylitis Radiology Index (BASRI)], yaşam kalitesi Nottingham Health Profile-1 (NHP) ve St. George Solunum Anketi (SGRQ), psikolojik semptomları ise Beck Depresyon Ölçeği (BDÖ) ile değerlendirildi. Bulgular: Hastaların %15.4'ünde (n: 3/1, restriktif/obstrüktif) solunum fonksiyon testlerinde bozukluk görüldü. Hastaların %20.9'unda (n: 5) YRBT'de akciğerde patolojik bulgu saptandı. FEV1 % ile BASFI (r=-0.56, p<0.01) arasında anlamlı negatif ilişki bulundu. Diğer solunum fonksiyon testleri ve YRBT ile hastalık süresi, Bath indeksleri, NHP, SGRQ ve BDÖ arasında anlamlı ilişki bulunmadı (p>0.05). Sonuç: Çalışmamızda sigara içmeyen, hastalık süresi uzun olan AS hastalarında pulmoner tutulumun görülebildiği ancak pulmoner tutulumun klinik, yaşam kalitesi ve psikolojik semptomlar üzerinde etkili olmadığı sonucuna varılmıştır
Objective: Pain and stiffness disturb the psychological status and quality of life in ankylosing spondylitis (AS) patients, which may be further deteriorated by pulmonary involvement. Therefore, detection of pulmonary involvement in AS patients is important. in this study, we aimed to detect pulmonary involvement in AS patients and to assess the effects of pulmonary involvement on Bath indexes, quality of life and psychological symptoms.Material and Methods: the study included 26 AS patients (mean age: 47.5±10.8 years). Pulmonary status of the patients was assessed by spirometric measurements and radiographic methods (chest X-ray, high resolution computerized tomography [HRCT]); clinical status was assessed by Bath indexes (Bath Ankylosing Spondylitis Disease Activity Index [BASDAI], Bath Ankylosing Spondylitis Functional Index [BASFI], Bath Spondylitis Metrology Index [BASMI], Bath Ankylosing Spondylitis Radiology Index [BASRI]); quality of life was assessed by Nottingham Health Profile-1 (NHP) and St. George Respiratory Questionnaire (SGRQ); and psychological symptoms were assessed by Beck Depression Scale (BDS). Results: Respiratory function tests were impaired in 15.4% of the patients (n: 3/1, restrictive/obstructive). HRCT revealed pathologic findings in 20.9% of the patients (n: 5). A negative correlation was detected between forced expiratory volume in 1 second (FEV1%) and BASFI (r=-0.56, p<0.01). No significant correlation was observed between the other respiratory function tests and HRCT, duration of disease, Bath indexes (BASDAI, BASFI, BASMI, BASRI), NHP, SGRQ, and BDS (p>0.05). Conclusion: Our study showed that pulmonary involvement may be observed among non-smoker AS patients with longer duration of disease; however, pulmonary involvement is not related with clinical status, quality of life or psychological symptoms
Objective: Pain and stiffness disturb the psychological status and quality of life in ankylosing spondylitis (AS) patients, which may be further deteriorated by pulmonary involvement. Therefore, detection of pulmonary involvement in AS patients is important. in this study, we aimed to detect pulmonary involvement in AS patients and to assess the effects of pulmonary involvement on Bath indexes, quality of life and psychological symptoms.Material and Methods: the study included 26 AS patients (mean age: 47.5±10.8 years). Pulmonary status of the patients was assessed by spirometric measurements and radiographic methods (chest X-ray, high resolution computerized tomography [HRCT]); clinical status was assessed by Bath indexes (Bath Ankylosing Spondylitis Disease Activity Index [BASDAI], Bath Ankylosing Spondylitis Functional Index [BASFI], Bath Spondylitis Metrology Index [BASMI], Bath Ankylosing Spondylitis Radiology Index [BASRI]); quality of life was assessed by Nottingham Health Profile-1 (NHP) and St. George Respiratory Questionnaire (SGRQ); and psychological symptoms were assessed by Beck Depression Scale (BDS). Results: Respiratory function tests were impaired in 15.4% of the patients (n: 3/1, restrictive/obstructive). HRCT revealed pathologic findings in 20.9% of the patients (n: 5). A negative correlation was detected between forced expiratory volume in 1 second (FEV1%) and BASFI (r=-0.56, p<0.01). No significant correlation was observed between the other respiratory function tests and HRCT, duration of disease, Bath indexes (BASDAI, BASFI, BASMI, BASRI), NHP, SGRQ, and BDS (p>0.05). Conclusion: Our study showed that pulmonary involvement may be observed among non-smoker AS patients with longer duration of disease; however, pulmonary involvement is not related with clinical status, quality of life or psychological symptoms
Açıklama
Anahtar Kelimeler
Romatoloji
Kaynak
Turkish Journal of Rheumatology(.)Archives of Rheumatology
WoS Q Değeri
Scopus Q Değeri
Cilt
24
Sayı
4
