Pauci-immune necrotizing crescentic glomerulonephritis with crescentic and full moon extracapillary proliferation: Clinico-pathologic correlation and follow-up study

Basit Öğe Kaydı
dc.contributor.authorUnlu, Mehtat
dc.contributor.authorKiremitci, Saba
dc.contributor.authorEnsari, Arzu
dc.contributor.authorOzluk, Yasemin
dc.contributor.authorKilicaslan, Isin
dc.contributor.authorOzdemir, Binnaz Handan
dc.contributor.authorAtes, Deniz
dc.contributor.authorBaydar, Dilek Ertoy
dc.contributor.authorGonul, Ipek Isik
dc.contributor.authorMemis, Leyla
dc.contributor.authorSarsik, Banu
dc.contributor.authorSen, Sait
dc.contributor.authorAkkaya, Bahar
dc.contributor.authorOrhan, Diclehan
dc.contributor.authorGonlusen, Gulfiliz
dc.contributor.authorEllidokuz, Hulya
dc.contributor.authorAda, Sibel
dc.contributor.authorCavdar, Caner
dc.contributor.authorAkagun, Tulin
dc.contributor.authorKamali, Sevil
dc.contributor.authorAksu, Kenan
dc.contributor.authorYazisiz, Veli
dc.contributor.authorPaydas, Saime
dc.contributor.authorSoylu, Alper
dc.contributor.authorSarioglu, Sulen
dc.date.accessioned2019-10-27T21:43:24Z
dc.date.available2019-10-27T21:43:24Z
dc.date.issued2013
dc.departmentEge Üniversitesien_US
dc.description.abstractThe prognostic value of the type and extent of extracapillary proliferation (ECP) in pauci-immune necrotizing crescentic glomerulonephitis (PIGN) was evaluated in this study. In 141 PIGN cases, all glomeruli with ECP were grouped according to type (cellular, fibrocellular and fibrous) and extent of the lesions in Bowman's space; (segmental, semicircumferential and circumferential, which might be termed full moon-FM). Cases with cellular and fibrous lesions involving >= 50% of glomeruli with ECP were classified as cellular and fibrous groups, respectively, while the remaining cases were classified as fibrocellular. Cases with segmental and circumferential (FM glomerulus) lesions involving >= 50% of glomeruli with ECP were classified as ECPI and ECPIII (FM) groups, respectively, while the rest were classified as ECPII. All the cases were classified according to Berden et al. Significant results were only nearly obtained for the FM group, including the need for dialysis. The Cox regression model revealed a 2.6-fold risk for FM cases regarding dialysis requirement. We propose that the percentage of FM glomeruli should be noted in the pathology report, and cases with more than 50% of FM glomeruli (FM group) should be identified in the group with increased risk of dialysis requirement. Our series also suggests that classification according to Berden et al. is of clinical relevance. (C) 2012 Elsevier GmbH. All rights reserved.en_US
dc.identifier.doi10.1016/j.prp.2012.10.012en_US
dc.identifier.endpage82en_US
dc.identifier.issn0344-0338
dc.identifier.issue2en_US
dc.identifier.pmid23246377en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage75en_US
dc.identifier.urihttps://doi.org/10.1016/j.prp.2012.10.012
dc.identifier.urihttps://hdl.handle.net/11454/47078
dc.identifier.volume209en_US
dc.identifier.wosWOS:000317162700002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Gmbh, Urban & Fischer Verlagen_US
dc.relation.ispartofPathology Research and Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectExtracapillary proliferationen_US
dc.subjectCrescenten_US
dc.subjectFull moonen_US
dc.subjectPrognosisen_US
dc.subjectPauci-immune necrotizing crescentic glomerulonephitisen_US
dc.titlePauci-immune necrotizing crescentic glomerulonephritis with crescentic and full moon extracapillary proliferation: Clinico-pathologic correlation and follow-up studyen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu