Experience with teicoplanin in the treatment of neonatal staphylococcal sepsis

Basit Öğe Kaydı
dc.contributor.authorYalaz M.
dc.contributor.authorCetin H.
dc.contributor.authorAkisu M.
dc.contributor.authorYeniay B.
dc.contributor.authorTunger A.
dc.contributor.authorKultursay N.
dc.date.accessioned2019-10-27T00:22:47Z
dc.date.available2019-10-27T00:22:47Z
dc.date.issued2004
dc.departmentEge Üniversitesien_US
dc.description.abstractWe aimed to evaluate retrospectively the clinical and bacteriological efficacy and potential side-effects of teicoplanin treatment in neonates with proven staphylococcal infection. There were 37 episodes of staphylococcal septicaemia in neonates with a mean gestational age of 34.2 ± 2.3 weeks; 26 were caused by coagulase-negative staphylococcal (CoNS) sepsis and 11 by Staphylococcus aureus sepsis. All episodes were treated with teicoplanin (intravenous loading dose 16 mg/kg followed by a maintenance dose of 8 mg/kg daily). The methicillin resistance and antibiotic susceptibilities of both micro-organisms were evaluated. Bacterial eradication was achieved in 89.1% of cases and mortality was 16.2%. The mean duration of treatment of the survivors was 11.6 ± 2.3 days. There were no drug-related adverse events and the biochemical and haematological tests showed no clinically significant changes in relation to teicoplanin therapy. Our results suggest that teicoplanin is highly effective in neonatal staphylococcal sepsis.en_US
dc.identifier.doi10.1177/147323000403200512en_US
dc.identifier.endpage548en_US
dc.identifier.issn0300-0605
dc.identifier.issue5en_US
dc.identifier.pmid15458287en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage540en_US
dc.identifier.urihttps://doi.org/10.1177/147323000403200512
dc.identifier.urihttps://hdl.handle.net/11454/22647
dc.identifier.volume32en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherCambridge Medical Publicationsen_US
dc.relation.ispartofJournal of International Medical Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNeonatalen_US
dc.subjectNewbornen_US
dc.subjectSepsisen_US
dc.subjectStaphylococcal infectionen_US
dc.subjectTeicoplaninen_US
dc.titleExperience with teicoplanin in the treatment of neonatal staphylococcal sepsisen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu