Comparison of anti-factorXa assay and rotational thromboelastogram in evaluating the efficacy of enoxaparine treatment in patients with acute coronary syndrome without ST-segment elevation

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dc.contributor.authorGunduz, Ramazan
dc.contributor.authorYildiz, Bekir Serhat
dc.contributor.authorOzdemir, Ibrahim Halil
dc.contributor.authorOzen, Mehmet Burak
dc.contributor.authorCetin, Nurullah
dc.contributor.authorYavuzgil, Oguz
dc.date.accessioned2023-01-12T20:11:25Z
dc.date.available2023-01-12T20:11:25Z
dc.date.issued2021
dc.departmentN/A/Departmenten_US
dc.description.abstractPurpose: The aim of this study was to compare anti-factor Xa assay and tromboelastogram in evaluation of efficacy of enoxaparin in patients with acute coronary syndrome without ST-segment elevation. Materials and Methods: Twenty-five patients with acute coronary syndrome were involved. Two blood samples were taken on admission and 4 hours after the subcutaneous injection of third dose of 1mg/kg enoxaparin to the patients. AntiFXa, tromboelastogram, activated coagulation time were calculated. Results: A non-significant increase in activated coagulation time was observed after the injection of enoxaparin. After injection enoxaparin thromboelastography parameters changed maximum amplitude(MA) increased (MA basal 65.4 +/- 11.9 after 63.4 +/- 7.8), R time increased (from 5 +/- 1.7 to 8.4 +/- 4.6,), K time increased (from 1.89 +/- 1.06 to 2.56 +/- 1.4), angle increased (from 66.34 +/- 5.6 to 57.9 +/- 11.4). AntiFXa increased. (from 0.122 +/- 0.06 to 0.501 +/- 0.359). Conclusion: Tromboelastography method can be used in assessment of efficacy of enoxaparin in patients with acute coronary syndrome without ST-Segment elevation.en_US
dc.identifier.doi10.17826/cumj.977136
dc.identifier.endpage1484en_US
dc.identifier.issn2602-3032
dc.identifier.issn2602-3040
dc.identifier.issue4en_US
dc.identifier.startpage1478en_US
dc.identifier.trdizinid468305en_US
dc.identifier.urihttps://doi.org/10.17826/cumj.977136
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/468305
dc.identifier.urihttps://hdl.handle.net/11454/78108
dc.identifier.volume46en_US
dc.identifier.wosWOS:000728748600020en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isotren_US
dc.publisherCukurova Univ, Fac Medicineen_US
dc.relation.ispartofCukurova Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEnoxaparinen_US
dc.subjecttromboelastogramen_US
dc.subjectacute coronary syndromeen_US
dc.subjectMolecular-Weight Heparinen_US
dc.subjectUnfractionated Heparinen_US
dc.subjectTherapyen_US
dc.subjectImpacten_US
dc.titleComparison of anti-factorXa assay and rotational thromboelastogram in evaluating the efficacy of enoxaparine treatment in patients with acute coronary syndrome without ST-segment elevationen_US
dc.typeArticleen_US

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