Telomeric restriction analysis of vascular smooth muscle cells following balloon angioplasty in rabbits

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dc.contributor.authorOzsarlak-Sozer, G.
dc.contributor.authorKerry, Z.
dc.contributor.authorOran, I.
dc.contributor.authorGokce, G.
dc.contributor.authorTosun, M.
dc.contributor.authorBechard, L.
dc.contributor.authorReel, B.
dc.contributor.authorYasa, M.
dc.contributor.authorLebe, B.
dc.contributor.authorTopcu, Z.
dc.date.accessioned2019-10-27T20:46:31Z
dc.date.available2019-10-27T20:46:31Z
dc.date.issued2009
dc.departmentEge Üniversitesien_US
dc.description.abstractG. OZSARLAK-SOZER, Z. KERRY, I. OR-AN, G. GOKCE, M. TOSUN, L. BECHARD, B. REEL, M. YASA, B. LEBE and Z. TOPCU. Telomeric restriction analysis of vascular smooth muscle cells following balloon angioplasty in rabbits. J Physiol Biochem, 65 (3), 243-250, 2009. Intimal hyperplasia due to smooth muscle cell proliferation and migration has been reported to be responsible for the pathogenesis of atherosclerosis and restenosis, manifested following balloon angioplasty. In this study, we employed the balloon angioplasty model to study telomere length regulation in proliferating vascular smooth muscle cells. Our results showed that balloon angioplasty in iliac arteries resulted in intimal hyperplasia due to proliferation of the smooth muscle cells and small size telomeric restrictional fragments were evident in injured arteries.en_US
dc.description.sponsorshipThe Scientific and Technological Research Council of TurkeyTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [SBAG-2787]; Ege University Science and Technology Research CenterEge University [05BIL005]; Ege University Research FoundEge University [04ECZ012]en_US
dc.description.sponsorshipThis study was supported by grants from The Scientific and Technological Research Council of Turkey (SBAG-2787, ZK), Ege University Science and Technology Research Center (05BIL005, ZK) and Ege University Research Found (04ECZ012, GOS). The authors thank Dr. M. J. McEachern for his comments on the manuscript.en_US
dc.identifier.doi10.1007/BF03180577en_US
dc.identifier.endpage249en_US
dc.identifier.issn1138-7548
dc.identifier.issn1877-8755
dc.identifier.issue3en_US
dc.identifier.pmid20119819en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage243en_US
dc.identifier.urihttps://doi.org/10.1007/BF03180577
dc.identifier.urihttps://hdl.handle.net/11454/42412
dc.identifier.volume65en_US
dc.identifier.wosWOS:000273857700004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofJournal of Physiology and Biochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectTelomere lengthen_US
dc.subjectTelomeraseen_US
dc.subjectBalloon angioplastyen_US
dc.subjectAtherosclerosisen_US
dc.titleTelomeric restriction analysis of vascular smooth muscle cells following balloon angioplasty in rabbitsen_US
dc.typeArticleen_US

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