Absorbed dose estimates at the cellular level for 131I

Küçük Resim Yok

Tarih

2005

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Microdosimetric calculations of 131I have been evaluated for a single cell and for cell clusters. A VsBasic program has been used to calculate stopping power, linear energy transfer, range values and deposited energies per decay for beta particles, Auger and conversion electrons of 131I. The chemical composition of the cell has been taken into account in this model; results were compared with water medium. Besides, total absorbed doses have been calculated for the radionuclides distributed randomly within the cell and clusters. Cross-fire irradiation has been considered for clusters of cells. In this case, absorbed doses per cell within a cluster were found to be significantly higher than absorbed doses per single cell, depending on the cluster size. Results showed that 131I is a promising radionuclide for therapy of tumors from millimeter to centimeter dimensions. © 2004 Published by Elsevier Ltd.

Açıklama

Anahtar Kelimeler

131I, Auger electrons, Beta particles, Cell, Internal conversion electrons, Microdosimetry

Kaynak

Applied Radiation and Isotopes

WoS Q Değeri

Scopus Q Değeri

Q3

Cilt

62

Sayı

6

Künye