Late endocrine side effects in children with acute leukemia
dc.contributor.author | Büyükavci M. | |
dc.contributor.author | Çetingül N. | |
dc.contributor.author | Darcan Ş. | |
dc.contributor.author | Kantar M. | |
dc.contributor.author | Kavakli K. | |
dc.date.accessioned | 2019-10-26T23:59:19Z | |
dc.date.available | 2019-10-26T23:59:19Z | |
dc.date.issued | 2007 | |
dc.department | Ege Üniversitesi | en_US |
dc.description.abstract | This study was carried out in 28 patients (10 female, 18 male) diagnosed with acute leukemia, and aimed to investigate the abnormalities of endocrine system. Twenty-five of 28 patients were acute lymphoblastic leukemia and 3 were acute non-lymphocytic leukemia. Sixteen children were treated using BFM-90 chemotherapy protocol, and the rest with various regimens. Two patients were exposed to 12-13 Gy of total body irradiation followed by bone marrow transplantation. All patients were in remission at least five years. One (3%) of 28 patients had short stature and 4 (14%) had obesity. Pubertal status was retarded in 2 (7%) patients. Glucose intolerance, secondary hypothyroidism and hypergonadotropic hypogonadism were detected in 2, 1 and 2 patients, respectively. TSH response to TRH test was exaggerated in 1 and blunted in 3 patients. © Turkish Society of Hematology. | en_US |
dc.identifier.endpage | 13 | en_US |
dc.identifier.issn | 1300-7777 | |
dc.identifier.issue | 1 | en_US |
dc.identifier.scopusquality | Q3 | en_US |
dc.identifier.startpage | 8 | en_US |
dc.identifier.uri | https://hdl.handle.net/11454/21374 | |
dc.identifier.volume | 24 | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.indekslendigikaynak | TR-Dizin | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Turkish Journal of Hematology | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Acute leukemia | en_US |
dc.subject | Children | en_US |
dc.subject | Endocrine | en_US |
dc.subject | Late side effects | en_US |
dc.title | Late endocrine side effects in children with acute leukemia | en_US |
dc.type | Article | en_US |