Late endocrine side effects in children with acute leukemia

dc.contributor.authorBüyükavci M.
dc.contributor.authorÇetingül N.
dc.contributor.authorDarcan Ş.
dc.contributor.authorKantar M.
dc.contributor.authorKavakli K.
dc.date.accessioned2019-10-26T23:59:19Z
dc.date.available2019-10-26T23:59:19Z
dc.date.issued2007
dc.departmentEge Üniversitesien_US
dc.description.abstractThis study was carried out in 28 patients (10 female, 18 male) diagnosed with acute leukemia, and aimed to investigate the abnormalities of endocrine system. Twenty-five of 28 patients were acute lymphoblastic leukemia and 3 were acute non-lymphocytic leukemia. Sixteen children were treated using BFM-90 chemotherapy protocol, and the rest with various regimens. Two patients were exposed to 12-13 Gy of total body irradiation followed by bone marrow transplantation. All patients were in remission at least five years. One (3%) of 28 patients had short stature and 4 (14%) had obesity. Pubertal status was retarded in 2 (7%) patients. Glucose intolerance, secondary hypothyroidism and hypergonadotropic hypogonadism were detected in 2, 1 and 2 patients, respectively. TSH response to TRH test was exaggerated in 1 and blunted in 3 patients. © Turkish Society of Hematology.en_US
dc.identifier.endpage13en_US
dc.identifier.issn1300-7777
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage8en_US
dc.identifier.urihttps://hdl.handle.net/11454/21374
dc.identifier.volume24en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Hematologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcute leukemiaen_US
dc.subjectChildrenen_US
dc.subjectEndocrineen_US
dc.subjectLate side effectsen_US
dc.titleLate endocrine side effects in children with acute leukemiaen_US
dc.typeArticleen_US

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