Retrospective Evaluation of COVID-19 Infection and COVID-19 Vaccines in Heart Transplant Patients
Küçük Resim Yok
Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Inc.
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background: Patients who have performed solid organ transplantation in terms of COVID-19 infection are included in the high-risk group. In this study, it was aimed to evaluate the relationship between vaccination and retrospective evaluation of 32 patients who underwent a heart transplant in the clinic and tested positive for SARS-CoV-2 polymerase chain reaction. Methods: In this study, demographic characteristics of the cases, comorbidities, timing of heart transplantation, immunosuppressive treatments, symptoms of COVID-19 infection, lung imaging findings, follow-up (outpatient/inpatient), treatments, 1-month mortality, and vaccination histories against COVID-19 infection were evaluated. The data obtained from the study were analyzed with SPSS version 25.0. Results: The 3 most common symptoms are cough (37.5%), myalgia (28.1%), and fever (21.8%). COVID-19 infection was severe in 6.2% of the patients, moderate in 37.5%, and mild in 56.2%. Hospitalization was required in 5 patients (15.6%, 1 in the intensive care unit), and the other patients were followed up as an outpatient. Severe COVID-19 infection was seen more in 33% of unvaccinated patients; 93.5% were vaccinated. Nineteen patients (68%) were vaccinated before COVID-19 infection. Our patients received the CoronoVac (Sinovac, China) vaccine. Conclusion: COVID-19 infection is more likely to be severe and mortal in patients with heart transplant recipients. It is also crucial to comply with preventive measures other than immunization in this group of patients. This study is the largest series investigating COVID-19 infection in heart transplant recipient patients in our country. © 2023 Elsevier Inc.
Açıklama
Anahtar Kelimeler
coronovac, SARS-CoV-2 vaccine, SARS-CoV-2 vaccine, adult, Article, clinical article, clinical feature, comorbidity, controlled study, coronavirus disease 2019, correlational study, coughing, data analysis, demographics, disease severity, female, fever, follow up, heart transplantation, hospitalization, human, immunosuppressive treatment, male, middle aged, mortality, myalgia, polymerase chain reaction, retrospective study, vaccination, coronavirus disease 2019, graft recipient, outpatient, Severe acute respiratory syndrome coronavirus 2, COVID-19, COVID-19 Vaccines, Heart Transplantation, Humans, Outpatients, Retrospective Studies, SARS-CoV-2, Transplant Recipients
Kaynak
Transplantation Proceedings
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
55
Sayı
5
