Seroprevalence of hepatitis B infection in the Turkish population in Northern Cyprus

Basit Öğe Kaydı
dc.contributor.authorKurugol, Zafer
dc.contributor.authorKoturoglu, Guelane
dc.contributor.authorAksit, Sadik
dc.contributor.authorOzacar, Tijen
dc.date.accessioned2019-10-27T20:19:19Z
dc.date.available2019-10-27T20:19:19Z
dc.date.issued2009
dc.departmentEge Üniversitesien_US
dc.description.abstractThis study was conducted to determine the seroprevalence of hepatitis B vir-us (HBV) infection in the Turkish population in Northern Cyprus. The secondary aim of this study was to assess the impact of the universal infant hepatitis B vaccination program, which started in 1998. A total of 600 persons I to 30 years old were selected for the study with cluster sampling. The information on sociodemographic characteristics was gathered for each participant and in 585 of them, hepatitis B surface antigen (HBsAg), anti-hepatitis B surface antigen antibody (anti-HBs) and anticore antibody (anti-HBc) were tested. The overall prevalence of anti-HBc and HBsAg carriage was 13.2% and 0.85%, respectively. Old age and low parental educational level were the major independent risk factors for HBV transmission. Seroprevalence of both anti-HBc and anti-HBs antibodies was similar in children 1-7 years of age. After 8 years of age, anti-HBc seroprevalence increased significantly with age, while anti-HBs prevalence decreased (p<0.001). Anti-HBc prevalence increased from 7.0% in children aged 1-7 years to 17.9% in persons aged 16-20 years. None of the children under 12 years of age were HBsAg-positive, while 1.9% of persons aged 16-20 years were HBsAg carriers. Anti-HBs seroprevalence exceeding 90% was found in the cohorts targeted by the routine hepatitis B vaccination program, whereas 36.4% of young adults aged 21-30 years were anti-HBs-positive. The study shows that universal infant hepatitis B immunization has a substantial impact on the immunity in children. However, prevalence of HBV infection is still high in adolescent and young adults in Northern Cyprus. Therefore, catch-up immunization for these groups will help to reduce hepatitis B transmission.en_US
dc.identifier.endpage126en_US
dc.identifier.issn0041-4301
dc.identifier.issue2en_US
dc.identifier.pmid19480322en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage120en_US
dc.identifier.urihttps://hdl.handle.net/11454/41391
dc.identifier.volume51en_US
dc.identifier.wosWOS:000266291500005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish J Pediatricsen_US
dc.relation.ispartofTurkish Journal of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjecthepatitis B immunizationen_US
dc.subjectepidemiologyen_US
dc.subjectvaccineen_US
dc.titleSeroprevalence of hepatitis B infection in the Turkish population in Northern Cyprusen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu