Comparison of Preemptive Kidney Transplantation With Nonpreemptive Kidney Transplantation in a Single Center: A Follow-up Study

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dc.contributor.authorUnsal, M. G.
dc.contributor.authorYilmaz, M.
dc.contributor.authorSezer, T.
dc.contributor.authorCeltik, A.
dc.contributor.authorUnalp, O. V.
dc.contributor.authorUguz, A.
dc.contributor.authorAlci, E.
dc.contributor.authorTamer, A. F.
dc.contributor.authorHoscoskun, C.
dc.contributor.authorToz, H.
dc.date.accessioned2019-10-27T20:24:38Z
dc.date.available2019-10-27T20:24:38Z
dc.date.issued2015
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground and Aim. The effect of preemptive transplantation of kidneys from living donors on patient and allograft survival is controversial. In this study, we aimed to evaluate whether preemptive kidney transplantation performed without the development of patient dialysis-related complications has a favorable effect on patient and graft survival. Patients and Method. The study included 334 adult renal transplant recipients. Patients who underwent renal transplantation between January 2008 and December 2012 at a tertiary referral teaching hospital were followed, and outcomes were obtained by retrospective chart review. A total of 244 patients underwent dialysis before renal transplantation, whereas 90 patients underwent preemptive transplantation. Results. There were no significant differences between the 2 groups with regard to patients and graft survival rates (P > .05). Patient survival rates in preemptive and nonpreemptive groups were 98.9% and 96.3% in the first year, respectively (P = .199). Graft survival rates in preemptive and nonpreemptive groups were 96.7% and 93.0% in the first year, respectively (P = .163). Patient survival rates in preemptive and nonpreemptive groups were 98.9% and 95.7% in the third year, respectively (P = .155). Graft survival rates in preemptive and nonpreemptive groups were 93.5% and 88.5% in the third year, respectively (P = .138). There was a significant difference among years with regard to ratio of patients with preemptive transplantation (P = .009). The ratio was 17.5% in 2008, whereas it rose to 43.1% in 2012. Conclusion. Although preemptive kidney transplantation does not provide a significant patient and allograft survival advantage compared to nonpreemptive kidney transplantation, both therapeutic modalities provide good outcomes. Preemptive kidney transplantation has been an increasingly frequent renal replacement therapy option in recent years.en_US
dc.identifier.doi10.1016/j.transproceed.2015.04.039en_US
dc.identifier.endpage1387en_US
dc.identifier.issn0041-1345
dc.identifier.issn1873-2623
dc.identifier.issue5en_US
dc.identifier.pmid26093724en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1385en_US
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2015.04.039
dc.identifier.urihttps://hdl.handle.net/11454/42153
dc.identifier.volume47en_US
dc.identifier.wosWOS:000357066800036en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleComparison of Preemptive Kidney Transplantation With Nonpreemptive Kidney Transplantation in a Single Center: A Follow-up Studyen_US
dc.typeArticleen_US

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