Neuropsychological outcome in cases with acute disseminated encephalomyelitis

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dc.contributor.authorSerin, Hepsen
dc.contributor.authorŞimşek, Erdem
dc.contributor.authorKanmaz, Seda
dc.contributor.authorYılmaz, Sanem
dc.contributor.authorAktan, Gül
dc.contributor.authorTekgül, Hasan
dc.contributor.authorGökben, Sarenur
dc.date.accessioned2023-01-12T20:29:58Z
dc.date.available2023-01-12T20:29:58Z
dc.date.issued2020
dc.departmentN/A/Departmenten_US
dc.description.abstractBackground and objectives. Acute disseminated encephalomyelitis (ADEM) is an immune-mediated, inflammatory and demyelinating disorder of the central nervous system. There have been a few studies in recent years on the fact that these cases have neurocognitive impairment. The purpose of this study is to evaluate the neurocognitive outcome and quality of life in cases with ADEM. Methods. Eleven cases who were on follow-up between 2008 and 2017 were included in the study, systemic, neurological and psychiatric examinations were done. All magnetic resonance images were re-evaluated. The neuropsychiatric evaluation was performed by clinical examination and psychometric scales; (1) The Pediatric Quality of Life Inventory 4.0, (2) Child Behavior Checklist, (3) Children’s Depression Inventory, (4) The Wechsler Intelligence Scale for Children-Revised and (5) Continuous Performance Test. The cases in our study underwent neuropsychiatric evaluation 3-42 months after the diagnosis of ADEM had been established. Results. Nine cases (81.8%) fully recovered without neurologic deficit. One case (9.1%) had a psychiatric disorder. During follow-up, cognitive and psychiatric problems were encountered in half of the cases (54.5%). Most of the cases with basal ganglia involvement (80%) displayed attention deficit and cognitive problems. Conclusion. In particular, cases with basal ganglia involvement should be followed carefully in terms of attention and cognitive problems.en_US
dc.identifier.doi10.24953/turkjped.2020.04.009
dc.identifier.endpage605en_US
dc.identifier.issn0041-4301
dc.identifier.issue4en_US
dc.identifier.startpage594en_US
dc.identifier.trdizinid516698en_US
dc.identifier.urihttps://doi.org/10.24953/turkjped.2020.04.009
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/516698
dc.identifier.urihttps://hdl.handle.net/11454/80685
dc.identifier.volume62en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Pediatricsen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleNeuropsychological outcome in cases with acute disseminated encephalomyelitisen_US
dc.typeArticleen_US

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