Diffusion tensor imaging in anorectal malformations: a pilot study for the evaluation of lumbosacral plexus

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dc.authorscopusid36877086200
dc.authorscopusid57191960544
dc.authorscopusid24824386400
dc.authorscopusid35236739700
dc.authorscopusid57531933100
dc.authorscopusid6603762840
dc.authorscopusid6701613383
dc.contributor.authorTiryaki, Sibel
dc.contributor.authorCeltik, Ulgen
dc.contributor.authorEraslan, Cenk
dc.contributor.authorDivarci, Emre
dc.contributor.authorTekin, Ali
dc.contributor.authorOzok, Geylani
dc.contributor.authorErgun, Orkan
dc.date.accessioned2023-01-12T19:50:09Z
dc.date.available2023-01-12T19:50:09Z
dc.date.issued2022
dc.departmentN/A/Departmenten_US
dc.description.abstractIntroduction Neurogenic bladder with anorectal malformations (ARM) is a well-known yet understudied topic. Diffusion tensor imaging (DTI) is a special usage of MRI that can evaluate peripheric nerves. The aim of this study is to evaluate the lumbosacral plexuses of patients with ARM using DTI. Patients and methods Patients with ARM willing to participate were included. Patient files were reviewed, a questionnaire was made, and DTI was performed. Fractional anisotropy (FA) and apparent diffusion coefficient (ADC) were computed for the right and left lumbosacral plexuses. Results There were 18 patients and 12 controls. Groups were similar in terms of sex (p = 0.232) and age (p = 0.853). There was a significant difference only for ADC of the left plexus. There was visible asymmetry in tractographies and DTI parameters of two patients with severely deformed pelvises (image 1) but also in another patient with a normal sacrum. In addition, despite asymmetry, FA and ADC were similar to controls also in these patients. Conclusion This is the first study presenting quantitative data about the lumbosacral plexus in ARM. We think the most interesting finding of this study was observing the normal values even in the patients with severely malformed sacrum which is yet to be validated with further studies.en_US
dc.description.sponsorshipAliye Uster Foundation (Izmir, Turkey) research scholarship; research activities in Ege Universityen_US
dc.description.sponsorshipThis work was supported by Aliye Uster Foundation (Izmir, Turkey) research scholarship. This is an independent organization funding educational and research activities in Ege University. The authors have no conflict of interest regarding the study.en_US
dc.identifier.doi10.1007/s00383-022-05077-3
dc.identifier.endpage616en_US
dc.identifier.issn0179-0358
dc.identifier.issn1437-9813
dc.identifier.issue4en_US
dc.identifier.pmid35129658en_US
dc.identifier.scopus2-s2.0-85124253173en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage609en_US
dc.identifier.urihttps://doi.org/10.1007/s00383-022-05077-3
dc.identifier.urihttps://hdl.handle.net/11454/76030
dc.identifier.volume38en_US
dc.identifier.wosWOS:000752157900002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofPediatric Surgery Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnorectal malformationen_US
dc.subjectLumbosacral plexusen_US
dc.subjectNeurogenic bladderen_US
dc.subjectIncontinenceen_US
dc.subjectDiffusion tensor imagingen_US
dc.subjectMagnetic resonance imagingen_US
dc.subjectSacral Plexusen_US
dc.subjectChildrenen_US
dc.subjectContinenceen_US
dc.titleDiffusion tensor imaging in anorectal malformations: a pilot study for the evaluation of lumbosacral plexusen_US
dc.typeArticleen_US

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