Daily use of consensus interferon: One-year treatment results for chronic hepatitis C patients relapsing or non-responding to previous interferon

Basit Öğe Kaydı
dc.contributor.authorKarasu Z.
dc.contributor.authorGurakar A.
dc.contributor.authorJazzar A.
dc.contributor.authorWright H.
dc.date.accessioned2019-10-27T00:25:53Z
dc.date.available2019-10-27T00:25:53Z
dc.date.issued2000
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground/aim: The optimal dose, duration and frequency of interferon treatment for chronic hepatitis C is not clear. Preliminary hepatitis C virus kinetic studies have suggested that daily interferon is more advantageous than thrice in a week administration. Recently, a synthetic recombinant interferon, consensus interferon, has been approved for clinical application. There is no data available about daily use of consensus interferon. Methods: Our study protocol was designed to investigate the efficacy of long-term (12 month) daily consensus interferon therapy for chronic hepatitis C patients, who have either relapsed or not responded to previous interferon therapy. Eleven patients were included in the study. Results: Overall, eight (72%) patients became serum HCV-RNA negative. Of these, 60% (3/5) were among previous non-responders and 83% (5/6) were among previous relapsers. Conclusions: Our preliminary data suggests that daily use of consensus interferon provides encouraging results in relapsers and non-responders. However, further time is needed to evaluate the sustained response rate.en_US
dc.identifier.endpage195en_US
dc.identifier.issn1300-4948
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage191en_US
dc.identifier.urihttps://hdl.handle.net/11454/23318
dc.identifier.volume11en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectConsensus interferonen_US
dc.subjectHepatitis Cen_US
dc.titleDaily use of consensus interferon: One-year treatment results for chronic hepatitis C patients relapsing or non-responding to previous interferonen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu