Does minimed 780G™ insulin pump system affect energy and nutrient intake?: long-term follow-up study

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dc.authoridAtik-Altınok, Yasemin/0000-0001-5851-1012
dc.authoridMansuroglu, Yelda/0000-0002-3183-5217
dc.contributor.authorAtik-Altinok, Yasemin
dc.contributor.authorMansuroglu, Yelda
dc.contributor.authorDemir, Gunay
dc.contributor.authorBalki, Hanife Gul
dc.contributor.authorOzen, Samim
dc.contributor.authorDarcan, Sukran
dc.contributor.authorGoksen, Damla
dc.date.accessioned2024-08-31T07:47:28Z
dc.date.available2024-08-31T07:47:28Z
dc.date.issued2024
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective: We evaluate the energy and nutrient intake of children, adolescents, and young adults with type 1 diabetes (T1D) who started to use automated insulin delivery (AID) systems before the transition and during follow-up for 6 months in a real-world setting. Research design and methods: Twenty-nine people with T1D (PwD) who started to use MiniMed 780G (TM) participated in the study. Participants' 3-day food diaries and glycemic outcomes were analyzed at baseline and after (the 3(rd) and 6(th) month) switching to an advanced hybrid closed-loop system (a-HCL). Results: Mean carbohydrate, protein, and fat intake (energy %) at baseline were 49.1 +/- 4.5, 17.8 +/- 2.3, and 33.0 +/- 3.9, respectively, and there were no statistically significant differences during the follow-up period. However, low fiber (<14 g/1000 kcal) and high saturated fat (>10 energy %) intake in PwD, both baseline and follow-up period. The median auto-correction bolus ratio was 14.0 (9.5)% at auto mode after 14 days, 18.0 (11.0)% at the 3(rd) month, and 19.0 (7.5)% at the 6(th) month (p < 0.05). A negative correlation was present between auto-correction boluses with TIR in both the 3(rd) (r:-0.747, p < 0.01) and 6(th) month (r:-0.395, p < 0.05). A negative correlation was present between auto-correction boluses with TIR in both the 3(rd) (r:-0.747, p < 0.01) and 6(th) month (r:-0.395, p < 0.05). Conclusions: a-HCLS systems offer better glycemic control. Using the Minimed 780 G (TM) insulin pump system didn't change the energy and nutrient intake of PwD. This real-world follow-up study suggests that children, adolescents, and young adults with T1D consume saturated fat above and fiber intake lower than recommendations independent of the use of a-HCLS. Clinical trials registration number: NCT05666596.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkiye (TUBITAK)en_US
dc.description.sponsorshipOpen access funding provided by the Scientific and Technological Research Council of Turkiye (TUBITAK).en_US
dc.identifier.doi10.1038/s41430-024-01422-y
dc.identifier.endpage621en_US
dc.identifier.issn0954-3007
dc.identifier.issn1476-5640
dc.identifier.issue7en_US
dc.identifier.pmid38459160en_US
dc.identifier.scopus2-s2.0-85186872434en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage615en_US
dc.identifier.urihttps://doi.org/10.1038/s41430-024-01422-y
dc.identifier.urihttps://hdl.handle.net/11454/104424
dc.identifier.volume78en_US
dc.identifier.wosWOS:001181405600002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringernatureen_US
dc.relation.ispartofEuropean Journal of Clinical Nutritionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240831_Uen_US
dc.subjectBody-Mass Indexen_US
dc.subjectDiet Qualityen_US
dc.subjectChildrenen_US
dc.subjectAdolescentsen_US
dc.subjectYouthen_US
dc.subjectFaten_US
dc.titleDoes minimed 780G™ insulin pump system affect energy and nutrient intake?: long-term follow-up studyen_US
dc.typeArticleen_US

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