Evaluation of the Severity of Mitral Regurgitation by the Use of Signal Void in Magnetic Resonance Imaging

dc.contributor.authorOzdogan, Oner
dc.contributor.authorYuksel, Alper
dc.contributor.authorGurgun, Cemil
dc.contributor.authorKayikcioglu, Meral
dc.contributor.authorYavuzgil, Oguz
dc.contributor.authorCinar, Cahide Soydas
dc.date.accessioned2019-10-27T20:48:23Z
dc.date.available2019-10-27T20:48:23Z
dc.date.issued2009
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground: The study was designed to evaluate the severity of mitral regurgitation by cardiac magnetic resonance imaging (MRI). We proposed a new measurement of signal void by MRI and tried to define threshold values for the severity of regurgitation with different sequences. Methods: Twenty-one patients with mitral regurgitation were evaluated by echocardiography and MRI. We measured the length, width, and the area of jet flow void from long-axis and four-chamber views. The regurgitant area was measured with TrueFISP, FLASH sequences, and phase images by tracing the signal-void area in left atrium parallel to mitral annulus. This new parameter for grading of the severity of mitral regurgitation by cine MRI was called regurgitant area from short axis (RAFSA). Results: All methods (EROA, vena contracta) were correlated for determining the regurgitation severity (P < 0.01). There was a correlation between EROA by echocardiography and RAFSA by MRI with the TrueFISP, FLASH sequences, and phase images (P < 0.01). Stepwise regression analysis revealed that EROA was significantly correlated with RAFSA by phase images (P < 0.001). After regression analysis, threshold values of RAFSA by phase imaging were calculated and found to be 0.27 cm(2) and 0.92 cm(2) between mild, moderate, and severe mitral regurgitations (100% sensitivity, 67% specificity, and 100% sensitivity, 78% specificity, respectively) (P < 0.01, P < 0.05). Conclusions: MRI is an alternative method for evaluating mitral regurgitation. Our study suggests a new parameter, RAFSA by cine MRI, to grade the severity of mitral regurgitation and provides threshold values in order to define mild, moderate, and severe regurgitations. (ECHOCARDIOGRAPHY, Volume 26, November 2009)en_US
dc.identifier.doi10.1111/j.1540-8175.2009.00968.xen_US
dc.identifier.endpage1135en_US
dc.identifier.issn0742-2822
dc.identifier.issue10en_US
dc.identifier.pmid19725851en_US
dc.identifier.startpage1127en_US
dc.identifier.urihttps://doi.org/10.1111/j.1540-8175.2009.00968.x
dc.identifier.urihttps://hdl.handle.net/11454/42703
dc.identifier.volume26en_US
dc.identifier.wosWOS:000271778900002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWiley-Blackwell Publishing, Incen_US
dc.relation.ispartofEchocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniquesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectmitral regurgitationen_US
dc.subjectechocardiographyen_US
dc.subjectcardiac magnetic resonance imagingen_US
dc.titleEvaluation of the Severity of Mitral Regurgitation by the Use of Signal Void in Magnetic Resonance Imagingen_US
dc.typeArticleen_US

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