Treatment results of standalone XEN-45 implantation in patients with primary and secondary open-angle glaucoma

Basit Öğe Kaydı
dc.contributor.authorErbey, Meryem
dc.contributor.authorBarış, Mine
dc.contributor.authorAteş, Halil
dc.contributor.authorYılmaz, Suzan Güven
dc.date.accessioned2024-08-31T07:31:10Z
dc.date.available2024-08-31T07:31:10Z
dc.date.issued2022
dc.departmentEge Üniversitesien_US
dc.description.abstractPurpose: The purpose of this study was to evaluate the treatment results and complications of XEN-45 microstent implan- tation in open-angle glaucoma. Methods: In this study, 17 eyes of 17 patients who underwent XEN-45 implantation with 0.2 mg/cc mitomycin-c between June 2016 and February 2018 were retrospectively examined. Pre- and post-operative best-corrected visual acuity (BCVA), intraocular pressure (IOP), number of antiglaucomatous drugs, endothelial cell count (ECC), retinal nerve fiber layer (RNFL) thickness, number of post-operative needlings, and post-operative complications were evaluated. Results: The mean age of the patients (11 M, 6 F) was 62.6±19.8 (29–94) years and mean follow-up period was 16.8±3.5 (12–21) months. The mean IOP which was 27.6±6.0 (21–40) mmHg before glaucoma surgery decreased significantly to 14.1±3.3 3.4 (8–20) mmHg at the last visit (p<0.001). The number of antiglaucomatous drugs was 3.9±0.8 (2–5) preopera- tively and 1.7±1.3 (0–3) at the final examination (p=0.001). Pre-operative BCVA was 0.78±0.99 LogMAR and 0.8±0.99 LogMAR at the last visit (Wilcoxon test, p=0.99). The ECC was 2356.8±533.3 (1635–3275) cells/mm2 preoperatively and 2338.7±472.7 (1712–3178) cells/mm2 at the last visit and did not show statistically significant difference (p=0.470). The pre- and post-op- erative RNFL thickness measurements were 61.4±11.8 (43–82) ?m and 61.3±11.5 (45–82) ?m at the last visit, respectively (p=0.764). Needling was required in 4 (23.5%) eyes. Post-operative complications were observed in four eyes (23.5%). In the early post-operative period (?1 month), shallow anterior chamber and hypotony were detected in 1 eye and were treated medically. As late complications (>1 month), Tenon’s cyst in two eyes and fibrotic bleb in one eye were observed. Conclusion: XEN-45 implant surgery in open-angle glaucoma patients is an effective surgical procedure for IOP control. With preserved visual acuity and ECC, causing no devastating complications, it can also be considered as a very safe option in open-angle glaucoma cases.en_US
dc.identifier.doi10.14744/eer.2022.19484
dc.identifier.endpage34en_US
dc.identifier.issn2757-8135
dc.identifier.issn2757-9816
dc.identifier.issue4en_US
dc.identifier.startpage29en_US
dc.identifier.trdizinid1175362en_US
dc.identifier.urihttps://doi.org/10.14744/eer.2022.19484
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1175362
dc.identifier.urihttps://hdl.handle.net/11454/103340
dc.identifier.volume2en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofEuropean eye researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240831_Uen_US
dc.subjectGlaucoma surgery surgical outcomeen_US
dc.subjectopen-angle glaucomaen_US
dc.subjectXEN-45 implant.en_US
dc.titleTreatment results of standalone XEN-45 implantation in patients with primary and secondary open-angle glaucomaen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu