Apolipoprotein E ?4 allele and neurobehavioral status after on-pump coronary artery bypass grafting

dc.contributor.authorAskar F.Z.
dc.contributor.authorCetin H.Y.
dc.contributor.authorKumral E.
dc.contributor.authorCetin O.
dc.contributor.authorAcarer A.
dc.contributor.authorKosova B.
dc.contributor.authorYagdi T.
dc.date.accessioned2019-10-27T08:59:16Z
dc.date.available2019-10-27T08:59:16Z
dc.date.issued2005
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground and Aim: The presence of apolipoprotein E ?4 allele is being considered as a risk factor for cognitive decline after cardiac surgery. We sought the effect of apolipoprotein E ?4 allele on neurobehavioral status after on-pump coronary artery bypass grafting. Methods: Prior to the operation, neurologic examination and neurobehavioral cognitive status test (COGNISTAT) were performed. Both procedures were repeated on the day of discharge and 3 months after surgery. Apolipoprotein E ?4 allele positive and apolipoprotein E ?4 allele negative patients' performance on COGNISTAT were compared. Results: There was no statistically significant demographic and operative data difference between two groups. No neurological impairment was observed on examinations. There was no statistically significant neurocognitive decline difference between two groups' postoperative performances. Conclusions: It seems that apolipoprotein E ?4 allele may not affect neurobehavioral status in the intermediate period after on-pump coronary artery bypass grafting.en_US
dc.identifier.doi10.1111/j.1540-8191.2005.2004138.xen_US
dc.identifier.endpage505en_US
dc.identifier.issn0886-0440
dc.identifier.issue5en_US
dc.identifier.pmid16153291en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage501en_US
dc.identifier.urihttps://doi.org/10.1111/j.1540-8191.2005.2004138.x
dc.identifier.urihttps://hdl.handle.net/11454/27742
dc.identifier.volume20en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofJournal of Cardiac Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleApolipoprotein E ?4 allele and neurobehavioral status after on-pump coronary artery bypass graftingen_US
dc.typeArticleen_US

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