Neuropsychological outcome in cases with acute disseminated encephalomyelitis

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dc.contributor.authorKanmaz, Seda
dc.contributor.authorKose, Sezen
dc.contributor.authorEraslan, Cenk
dc.contributor.authorSimsek, Erdem
dc.contributor.authorSerin, Hepsen Mine
dc.contributor.authorYilmaz, Sanem
dc.contributor.authorGokben, Sarenur
dc.date.accessioned2020-12-01T11:59:08Z
dc.date.available2020-12-01T11:59:08Z
dc.date.issued2020
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground and objectives. Acute disseminated encephalomyelitis (ADEM) is an immune-mediated, inflammatory and demyelinating disorder of the central nervous system. There have been a few studies in recent years on the fact that these cases have neurocognitive impairment. the purpose of this study is to evaluate the neurocognitive outcome and quality of life in cases with ADEM. Methods. Eleven cases who were on follow-up between 2008 and 2017 were included in the study, systemic, neurological and psychiatric examinations were done. All magnetic resonance images were re-evaluated. the neuropsychiatric evaluation was performed by clinical examination and psychometric scales; (1) the Pediatric Quality of Life Inventory 4.0, (2) Child Behavior Checklist, (3) Children's Depression Inventory, (4) the Wechsler Intelligence Scale for Children-Revised and (5) Continuous Performance Test. the cases in our study underwent neuropsychiatric evaluation 3-42 months after the diagnosis of ADEM had been established. Results. Nine cases (81.8%) fully recovered without neurologic deficit. One case (9.1%) had a psychiatric disorder. During follow-up, cognitive and psychiatric problems were encountered in half of the cases (54.5%). Most of the cases with basal ganglia involvement (80%) displayed attention deficit and cognitive problems. Conclusion. in particular, cases with basal ganglia involvement should be followed carefully in terms of attention and cognitive problems.en_US
dc.identifier.doi10.24953/turkjped.2020.04.009en_US
dc.identifier.endpage605en_US
dc.identifier.issn0041-4301
dc.identifier.issue4en_US
dc.identifier.pmid32779412en_US
dc.identifier.scopus2-s2.0-85089334050en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage594en_US
dc.identifier.urihttps://doi.org/10.24953/turkjped.2020.04.009
dc.identifier.urihttps://hdl.handle.net/11454/62190
dc.identifier.volume62en_US
dc.identifier.wosWOS:000559511900009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish J Pediatricsen_US
dc.relation.ispartofTurkish Journal of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectADEMen_US
dc.subjectneuroimagingen_US
dc.subjectneuropsychiatric disordersen_US
dc.titleNeuropsychological outcome in cases with acute disseminated encephalomyelitisen_US
dc.typeArticleen_US

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