Comparative Evaluation of Polyphenol Contents and Biological Activities of Five Cistus L. Species Native to Turkey

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dc.authoridBaykan, Sura/0000-0002-3624-4811
dc.authoridONAL, Fatma Nur/0000-0002-6574-1905
dc.authoridKose, Fadime Aydin/0000-0001-5222-7555
dc.authoridKose, Fadime Aydin/0000-0001-5222-7555
dc.authorscopusid58040913300
dc.authorscopusid55823702000
dc.authorscopusid40361182600
dc.authorscopusid58040622400
dc.authorscopusid6603402979
dc.authorscopusid23767071300
dc.authorwosidBaykan, Sura/IXX-2177-2023
dc.authorwosidONAL, Fatma Nur/IYJ-4239-2023
dc.authorwosidKose, Fadime Aydin/ACU-8190-2022
dc.authorwosidKose, Fadime Aydin/X-6550-2019
dc.contributor.authorÖnal, Fatma Nur
dc.contributor.authorÖztürk, İsmail
dc.contributor.authorAydın Köse, Fadime
dc.contributor.authorDer, Gülay
dc.contributor.authorKılınç, Emrah
dc.contributor.authorBaykan, Sura
dc.date.accessioned2024-08-25T18:47:29Z
dc.date.available2024-08-25T18:47:29Z
dc.date.issued2023
dc.departmentEge Üniversitesien_US
dc.description.abstractIn this study phytochemical compounds and antioxidant capacity, cytotoxic, antimicrobial and anti-biofilm activities of hydroethanolic extracts of five Cistus species (C. creticus L., C. laurifolius L., C. monspeliensis L., C. parviflorus Lam. and C. salviifolius L.) distributed in Turkey were investigated. (+)-catechin, epigallocatechin gallate, quercetin-3-O-rutinoside, quercetin-3-O-glucoside, kaempferol-3-O-glucoside, luteolin were detected in different amounts. Strongest antioxidant capacities were observed with C. creticus, and C. parvifolius (0.476 and 0.452, respectively). Minimum inhibitory concentrations (MIC) of the extracts were determined between 32 and 128 mu g/mL against different bacteria and Candida strains. C. monspeliensis and C. laurifolius extracts were inhibited the biofilm production levels of three Gram-negative bacteria (E. coli, S. enterica, P. aeruginosa), two Gram-positive bacteria (S. aureus, B. subtilis) and three Candida strains (C. albicans, C. parapsilosis, C. krusei). C. creticus extract showed strongest cytotoxic activity against human breast adenocarcinoma (MCF-7) and prostate cell lines (PC-3) (IC50: 14.04 +/- 2.78 mu g/mL and 34.04 +/- 2.74 mu g/mL, respectively) among all plants tested.en_US
dc.description.sponsorshipUniversity of Ege Department of Scientific Research Projects (BAP) [06/ECZ/015, TYL-2019-21061]en_US
dc.description.sponsorshipThis study was supported by the University of Ege Department of Scientific Research Projects (BAP, Project Number: 06/ECZ/015 and TYL-2019-21061).en_US
dc.identifier.doi10.1002/cbdv.202200915
dc.identifier.issn1612-1872
dc.identifier.issn1612-1880
dc.identifier.issue1en_US
dc.identifier.pmid36524294en_US
dc.identifier.scopus2-s2.0-85145460262en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1002/cbdv.202200915
dc.identifier.urihttps://hdl.handle.net/11454/101918
dc.identifier.volume20en_US
dc.identifier.wosWOS:000906443700001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWiley-V C H Verlag Gmbhen_US
dc.relation.ispartofChemistry & Biodiversityen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240825_Gen_US
dc.subjectCistusen_US
dc.subjectHPLCen_US
dc.subjectantioxidant activityen_US
dc.subjectcytotoxicityen_US
dc.subjectantimicrobial activityen_US
dc.subjectanti-biofilm activityen_US
dc.subjectLabdane-Type Diterpenesen_US
dc.subjectFolk Medicinal-Plantsen_US
dc.subjectAntioxidant Propertiesen_US
dc.subjectTraditional Medicineen_US
dc.subjectCytotoxic Activityen_US
dc.subjectExtractsen_US
dc.subjectLaurifoliusen_US
dc.subjectLeavesen_US
dc.subjectFlavonoidsen_US
dc.subjectResistanceen_US
dc.titleComparative Evaluation of Polyphenol Contents and Biological Activities of Five Cistus L. Species Native to Turkeyen_US
dc.typeArticleen_US

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