Evaluation of therapeutics management patterns and glycemic control of pediatric type 1 diabetes mellitus patients in Turkey: A nationwide cross-sectional study

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dc.contributor.authorHatun, Sukru
dc.contributor.authorDemirbilek, Huseyin
dc.contributor.authorDarcan, Sukran
dc.contributor.authorYuksel, Aysegul
dc.contributor.authorBinay, Cigdem
dc.contributor.authorSimsek, Damla Goksen
dc.contributor.authorKara, Cengiz
dc.contributor.authorCetinkaya, Ergun
dc.contributor.authorUnuvar, Tolga
dc.contributor.authorUcakturk, Ahmet
dc.contributor.authorTutunculer, Filiz
dc.contributor.authorCesur, Yasar
dc.contributor.authorBundak, Ruveyde
dc.contributor.authorSaglam, Halil
dc.contributor.authorSimsek, Enver
dc.contributor.authorBereket, Abdullah
dc.date.accessioned2019-10-27T23:08:54Z
dc.date.available2019-10-27T23:08:54Z
dc.date.issued2016
dc.departmentEge Üniversitesien_US
dc.description.abstractAims: To evaluate the management strategies, glycemic control and complications of pediatric type 1 diabetes mellitus (T1DM) patients in Turkey. Methods: Study included 498 patients with T1DM between the ages 1-18. Data provided from patients' hospital files were recorded on standard case report forms by applicant clinicians within the 3 months of data collection period between October 2012 and July 2013. Results: Mean age of patients was 11.3 +/- 3.8 years. Mean duration of DM was determined as 3.7 +/- 3.1 years. Majority of patients (85.5%) used basal/bolus injection (BBI), and 6.5% used continuous subcutaneous insulin infusion pump. Assessment of glycemic control based on HbA1c levels showed that 29.1% of patients had an HbA1c value <7.5% (58 mmol/mol), 16.1% had a value between 7.5% (58 mmol/mol) and 8% (64 mmol/mol), 19.1% had a value between 8.1% (64 mmol/mol) and 9%(75 mmol/mol) and 35.7% a value >9%(75 mmol/mol). Hypoglycemia was reported in 145 (29.1%) patients and the number of severe hypoglycemic attacks in the last 3 months was 1.0 +/- 2.4. Taking into consideration the carbohydrate count and insulin correction dose and parents with high socioeconomic status was related to have better glycemic control. The most common comorbidities were Hashimoto's thyroiditis/hypothyroidism (6.2%) followed by celiac disease (3.8%), epilepsy(1.2%), and asthma(1.0%). Conclusions: BBI insulin therapy is widely used among pediatric T1DM patients in Turkey. However, despite improvements in treatment facilities and diabetic care, glycemic control is not at a satisfactory level. Therefore, new and comprehensive initiatives require for pediatric T1DM patients with poor glycemic control. Promoting use of carbohydrate count and insulin correction doses may improve the glycemic control of pediatric T1DM in Turkey. (C) 2016 Elsevier Ireland Ltd. All rights reserved.en_US
dc.description.sponsorshipSanofiSanofi-Aventisen_US
dc.description.sponsorshipStudy was funded by Sanofi.en_US
dc.identifier.doi10.1016/j.diabres.2016.04.059en_US
dc.identifier.endpage40en_US
dc.identifier.issn0168-8227
dc.identifier.issn1872-8227
dc.identifier.pmid27423071en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage32en_US
dc.identifier.urihttps://doi.org/10.1016/j.diabres.2016.04.059
dc.identifier.urihttps://hdl.handle.net/11454/52416
dc.identifier.volume119en_US
dc.identifier.wosWOS:000381646900004en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Ireland Ltden_US
dc.relation.ispartofDiabetes Research and Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectType 1 diabetesen_US
dc.subjectChildrenen_US
dc.subjectTreatmenten_US
dc.subjectGlycemic controlen_US
dc.subjectHbA1cen_US
dc.titleEvaluation of therapeutics management patterns and glycemic control of pediatric type 1 diabetes mellitus patients in Turkey: A nationwide cross-sectional studyen_US
dc.typeArticleen_US

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