Pulmonary complications in heart transplant recipients

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dc.contributor.authorAtasever, A.
dc.contributor.authorBacakoglu, F.
dc.contributor.authorUysal, F. E.
dc.contributor.authorNalbantgil, S.
dc.contributor.authorYagdi, T.
dc.contributor.authorGuzelant, A.
dc.contributor.authorSayiner, A.
dc.date.accessioned2019-10-27T19:18:34Z
dc.date.available2019-10-27T19:18:34Z
dc.date.issued2006
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground. Heart transplantation is an important therapeutic option for patients with end-stage disease, but is associated with major pulmonary complications. Patients and methods. We retrospectively reviewed the posttransplant follow-up of 34 orthotopic heart transplant recipients. Results. Two of the 34 patients died of cardiac failure in the early postoperative period. Among the surviving patients, 10 (31.3%) developed pulmonary complications, all within the first 6 months: hospital-acquired bacterial pneumonia in five, fungal pneumonia in three, posttransplant lymphoproliferative disease in one, and community-acquired pneumonia in one patient. None of the patients developed transplantation-related malignancy. The overall mortality was 35.3%. Pneumonia-related mortality rate of 14.7% was due to early-onset nosocomial pneumonias, which were caused by bacterial and opportunistic microorganisms. Extrapulmonary causes of mortality were cardiac failure, meningitis, septicemia, and acute rejection. Cytomegalovirus antigenemia in the first month was associated with a poor prognosis. The frequency of pulmonary complications was higher among older patients and those who developed moderate rejection in the first month (P= .014 and P = .036, respectively). Conclusion. Pulmonary infections after heart transplantation occurred more frequently during the first 6 months posttransplantation, accounting for a significant portion of the posttransplantation mortality.en_US
dc.identifier.doi10.1016/j.transproceed.2006.02.098en_US
dc.identifier.endpage1534en_US
dc.identifier.issn0041-1345
dc.identifier.issn1873-2623
dc.identifier.issue5en_US
dc.identifier.pmid16797351en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1530en_US
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2006.02.098
dc.identifier.urihttps://hdl.handle.net/11454/38612
dc.identifier.volume38en_US
dc.identifier.wosWOS:000238700500086en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titlePulmonary complications in heart transplant recipientsen_US
dc.typeArticleen_US

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