The prognostic role of clinical, electroencephalographic and neuroradiological parameters in predicting outcome in pediatric non-traumatic coma

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dc.contributor.authorKitiş, Ömer
dc.contributor.authorYılmaz, Sanem
dc.contributor.authorAktan, Gül
dc.contributor.authorTekgül, Hasan
dc.contributor.authorGökben, Sarenur
dc.contributor.authorKarapınar, Bülent
dc.contributor.authorAnık, Ayşe
dc.date.accessioned2023-01-12T20:30:36Z
dc.date.available2023-01-12T20:30:36Z
dc.date.issued2020
dc.departmentN/A/Departmenten_US
dc.description.abstractPurpose: To investigate the early outcome of non-traumatic coma (NTC) in pediatric critical care in relation to the prognostic role of clinical, electroencephalographic, and neuro-radiological factors. Materials and methods: A total of 77 children (means of age: 70.5±68.7 months, 55.8% were boys) with acute encephalopathy, and NTC were included in this retrospective cross-sectional study. Data on patient demographics (age, gender, etiology of NTC) and prognostic factors [Glasgow coma scores (GCS), pupillary light reflex (PLR), electroencephalography (EEG) and cranial magnetic resonance imaging (MRI) findings] and neurological outcome (intensive care unit period and first 3 months after discharge) were recorded in each patient. Results: Hypoxic-ischemic encephalopathy (35.1%) and central nervous system infection (22.1%) were the most common etiologies in this study. The favorable and unfavorable neurological outcome was noted in 57% and 43% of patients, respectively. Lack of PLR (OR 3.09, 95% CI: 2.17 to 4.40, p<0.001), GCS ?5 (OR 7.85, 95% CI: 2.77 to 22.37, p<0.001), poor prognostic pattern in EEG (OR 13.76, 95% CI: 1.62 to 116.54, p=0.004) and presence of MRI lesions (OR 4.04, 95% CI: 1.15 to 14.19, p=0.029) were significant determinants of unfavorable neurological outcome. Conclusion: We conclude that combined use of clinical, EEG, and MRI findings might provide a more accurate estimation of neurological outcome in pediatric NTC.en_US
dc.identifier.doi10.31362/patd.685215
dc.identifier.endpage518en_US
dc.identifier.issn1309-9833
dc.identifier.issn1308-0865
dc.identifier.issue3en_US
dc.identifier.startpage509en_US
dc.identifier.trdizinid465610en_US
dc.identifier.urihttps://doi.org/10.31362/patd.685215
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/465610
dc.identifier.urihttps://hdl.handle.net/11454/80833
dc.identifier.volume13en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofPamukkale Tıp Dergisien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleThe prognostic role of clinical, electroencephalographic and neuroradiological parameters in predicting outcome in pediatric non-traumatic comaen_US
dc.typeArticleen_US

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