Antimicrobial and antioxidant activities with acute toxicity, cytotoxicity and mutagenicity of Cystoseira compressa (Esper) Gerloff & Nizamuddin from the coast of Urla (Izmir, Turkey)

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dc.contributor.authorGuner, Adem
dc.contributor.authorKoksal, Cinel
dc.contributor.authorErel, Sura Baykan
dc.contributor.authorKayalar, Husniye
dc.contributor.authorNalbantsoy, Ayse
dc.contributor.authorSukatar, Atakan
dc.contributor.authorYavasoglu, N. Ulku Karabay
dc.date.accessioned2019-10-27T22:30:30Z
dc.date.available2019-10-27T22:30:30Z
dc.date.issued2015
dc.departmentEge Üniversitesien_US
dc.description.abstractThe aim of the study was to evaluate the biological activities with toxic properties of the methanol, hexane, and chloroform extracts of Cystoseira compressa (Esper) Gerloff & Nizamuddin from the Coast of Urla in the Aegean Sea. The extracts of C. compressa were tested for their antimicrobial and antioxidant activities in this study. Cytotoxic and mutagenic potentials of the extracts were also evaluated using cell culture and mutagenicity assays. Hexane extract was found to have higher total flavonoid and phenolic contents than the other extracts and exerted higher antioxidant activity than other extracts. All extracts exhibited moderate antimicrobial activity against tested microorganisms (minimum inhibitory concentration ranges are 32-256 mu g/mL). The results indicated that the extracts had no significant cytotoxic activity against human hepatocellular carcinoma Hep 3B cell line in all treated concentrations (5-50 mu g/mL) and did not show mutagenicity in the Ames test. Lethality was not observed among mice treated with oral doses of the extracts. In conclusion, results of investigations indicate that brown alga C. compressa is a natural source of antioxidant. It has moderate antimicrobial activities with no toxicity.en_US
dc.identifier.doi10.1007/s10616-013-9668-xen_US
dc.identifier.endpage143en_US
dc.identifier.issn0920-9069
dc.identifier.issn1573-0778
dc.identifier.issue1en_US
dc.identifier.pmid24292649en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage135en_US
dc.identifier.urihttps://doi.org/10.1007/s10616-013-9668-x
dc.identifier.urihttps://hdl.handle.net/11454/51244
dc.identifier.volume67en_US
dc.identifier.wosWOS:000347948200014en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofCytotechnologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCystoseira compressaen_US
dc.subjectAntioxidant activityen_US
dc.subjectAntimicrobial activityen_US
dc.subjectAcute toxicityen_US
dc.subjectCytotoxicityen_US
dc.subjectMutagenicityen_US
dc.titleAntimicrobial and antioxidant activities with acute toxicity, cytotoxicity and mutagenicity of Cystoseira compressa (Esper) Gerloff & Nizamuddin from the coast of Urla (Izmir, Turkey)en_US
dc.typeArticleen_US

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