Epstein-Barr virus-related lymphoproliferative disorders in T-cell repleted haploidentical transplantation with post-transplant cyclophosphamide
Küçük Resim Yok
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer Japan Kk
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
EBV-associated lymphoproliferative disorders (LPDs) are common in hematopoietic stem cell transplantation (HSCT) with T-cell-depleted grafts, but are extremely rare in HSCT patients with T-cell-replete grafts with post-transplant cyclophosphamide (PTCy). Here we present the cases of two pediatric patients who developed EBV-related LPD after T-cell-replete haplo-HSCT with PTCy. One of these is the first reported case of EBV-positive mucocutaneous ulcer (EBVMCU) developing after PTCy. EBV-related diseases are rare in T-cell-replete haplo-HSCT patients with PTCy. However, in patients with risk factors, it is reasonable to screen for EBV viremia for LPD.
Açıklama
Anahtar Kelimeler
Post-transplant cyclophosphamide, Lymphoproliferative disorder, EBV-positive mucocutaneous ulcer, Epstein-Barr virus, Management, Blood
Kaynak
International Journal of Hematology
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
115
Sayı
4
