Çocukluk çağı kronik maksiller sinüzitinde nazal budesonidin etkinliği
Küçük Resim Yok
Tarih
1999
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
AMAÇ: Çocuklarda sinüs cerrahisine ait görülen erken ve geç komplikasyonlar nedeniyle kronik maksiller sinüzitte öncelikle tıbbi tedavi yöntemlerinin kullanılması önerilmektedir. Bu nedenle yeni ve daha etkin tıbbi tedavi yöntemleri araştırılmaktadır. Bu çalışmada kronik maksiller sinüzit tanısı alan çocuk hastalarda nazal topikal steroidin (budesonid) etkinliği araştırılmıştır. YÖNTEM: Çalışmaya yaşları 6-17yıl (ortalama 8.8±2.2 yıl) arasında değişen, allerji yada kronik bir solunum yolu patolojisi olmayan kronik maksiller sinüzit tanısı almış 19 erkek (% 56) ve 15 kız (% 44) olgu alınmıştır. 23 olguya nazal salin lavajı ve kısa süreli topikal dekonjestan yanında üç ay süreyle 200 mgr/gün nazal budesonid; kontrol grubu olarak alınan 11 olguya ise yalnızca nazal salin verilmiştir. BULGULAR: Olguların başlıca geliş yakınmaları üç ayın üzerinde devam eden öksürük (% 83), postnazal akıntı (% 58) ve başağrısı (% 47) olarak gözlenmiştir. Çalışma sonunda steroid grubundaki 15 olguda (% 65) klinik ve radyolojik tam düzelme elde edilmiştir. Kontrol grubunda ise kısmi klinik ve radyolojik düzelme saptanan 3 olgu dışında semptomlarda anlamlı düzelme gözlenmemiştir. SONUÇ: Bu sonuçlar bize çocukluk çağı KMS' de nazal steroidin etkin olduğunu ve cerrahi tedavi öncesi maksimal tıbbi tedavide alternatif olarak kullanılabileceğini düşündürmektedir.
AIM: Maximal medical therapy has been firstly suggested in the treatment of children with chronic maxillary sinusitis because the surgical methods cause several early and late complications. Therefore, many studies have been proposed to find new and more effective therapy modalities. the aim of this study was to investigate whether nasal topical steroid (budesonide) is effective in the treatment of children with chronic maxillary sinusitis. METHOD: Nineteen male (56%) and fifteen female (44) children aging between six and seventeen years old (mean age was 8.8±2.2 year) were enrolled to the study. the study group consisting of 23 children were treated by intranasal budesonide (200 mgr/day) plus nasal saline lavage and the control group consisting of 11 children were prescribed only nasal saline lavage for three months. RESULTS: Mainly complaints of subjects at the attendance were noted as prolonged cough more than three months (83 %), filling of postnasal dripping (58 %), headache (47 %). At the end of study, we observed clinical and also radiological complete remission in 15 children (65 %) treated by intranasal budesonide and partial remission in only three children of control group. CONCLUSION: Our results suggest that intranasal budesonide is safe and effective in the treatment of children with chronic maxillary sinusitis and it might be considered in maximally medical treatment before considering surgical intervention.
AIM: Maximal medical therapy has been firstly suggested in the treatment of children with chronic maxillary sinusitis because the surgical methods cause several early and late complications. Therefore, many studies have been proposed to find new and more effective therapy modalities. the aim of this study was to investigate whether nasal topical steroid (budesonide) is effective in the treatment of children with chronic maxillary sinusitis. METHOD: Nineteen male (56%) and fifteen female (44) children aging between six and seventeen years old (mean age was 8.8±2.2 year) were enrolled to the study. the study group consisting of 23 children were treated by intranasal budesonide (200 mgr/day) plus nasal saline lavage and the control group consisting of 11 children were prescribed only nasal saline lavage for three months. RESULTS: Mainly complaints of subjects at the attendance were noted as prolonged cough more than three months (83 %), filling of postnasal dripping (58 %), headache (47 %). At the end of study, we observed clinical and also radiological complete remission in 15 children (65 %) treated by intranasal budesonide and partial remission in only three children of control group. CONCLUSION: Our results suggest that intranasal budesonide is safe and effective in the treatment of children with chronic maxillary sinusitis and it might be considered in maximally medical treatment before considering surgical intervention.
Açıklama
Anahtar Kelimeler
Genel ve Dahili Tıp
Kaynak
Medical Network Klinik Bilimler ve Doktor
WoS Q Değeri
Scopus Q Değeri
Cilt
5
Sayı
6
