Diffuse Large B-Cell Lymphoma Arising in Warthin's Tumor: Case Study and Review of the Literature

dc.contributor.authorOzkok, Guliz
dc.contributor.authorTasli, Funda
dc.contributor.authorOzsan, Nazan
dc.contributor.authorOzturk, Rafet
dc.contributor.authorPostaci, Hakan
dc.date.accessioned2019-10-27T22:06:44Z
dc.date.available2019-10-27T22:06:44Z
dc.date.issued2013
dc.departmentEge Üniversitesien_US
dc.description.abstractWarthin's tumor is the second most common type of salivary gland tumor. Microscopically, Warthin's tumor displays a proliferative epithelial component and lymphoid stroma. Carcinomas arising from the epithelial component are well known, but malignant transformations of the lymphoid stroma are rare. When they do occur, they are most commonly B-cell type non-Hodgkin lymphomas. A 60-year-old male patient underwent surgical resection of a parotid mass. After superficial parotidectomy, microscopic examination indicated that the tumor was of epithelial components with basaloid and oncocytic columns of cells neighboring lymphoid components. In addition to the lymphoid follicles with distinct germinal centers, there were large, bizarre and extremely atypical neoplastic cells seen in the lymphoid component. Large neoplastic cells were diffusely CD20 and CD30 positive. The patient was diagnosed with "Warthin's tumor and diffuse large B-cell lymphoma with expression of CD30." The histopathologic and clinical features are discussed along with a review of the literature.en_US
dc.identifier.doi10.4132/KoreanJPathol.2013.47.6.579en_US
dc.identifier.endpage582en_US
dc.identifier.issn1738-1843
dc.identifier.issue6en_US
dc.identifier.pmid24421853en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage579en_US
dc.identifier.urihttps://doi.org/10.4132/KoreanJPathol.2013.47.6.579
dc.identifier.urihttps://hdl.handle.net/11454/48870
dc.identifier.volume47en_US
dc.identifier.wosWOS:000329533600012en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKorean Society Pathologistsen_US
dc.relation.ispartofKorean Journal of Pathologyen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectParotid glanden_US
dc.subjectAdenolymphomaen_US
dc.subjectLymphomaen_US
dc.subjectlarge B cellen_US
dc.subjectdiffuseen_US
dc.titleDiffuse Large B-Cell Lymphoma Arising in Warthin's Tumor: Case Study and Review of the Literatureen_US
dc.typeReview Articleen_US

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