Coronary tortuosity affects left ventricular myocardial functions: a 3D-speckle tracking echocardiography study

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dc.contributor.authorDogdus, Mustafa
dc.contributor.authorDemir, Emre
dc.contributor.authorCinar, Cahide Soydas
dc.contributor.authorGurgun, Cemil
dc.date.accessioned2020-12-01T12:01:51Z
dc.date.available2020-12-01T12:01:51Z
dc.date.issued2020
dc.departmentEge Üniversitesien_US
dc.description.abstractCoronary artery tortuosity (CAT) is a common finding in coronary angiography, and is defined as three fixed bends during both systole and diastole in at least one epicardial coronary artery, with each bend showing a 45 degrees change in vessel direction. the impact of CAT on the myocardial deformation has not been completely evaluated using 3D-STE. As a result of this, we aimed to assess the effects of CAT on LV functions using 3D-STE in the present study. Eighty-two patients with CAT and 80 age- and gender-matched controls who proved to have normal coronary angiograms were enrolled into the study. 3D-STE was performed and LV-GLS, LV-GCS, LV-GAS, and LV-GRS were obtained for every patient after coronary angiography. the LV-GLS was significantly depressed in the CAT ( +) group than in the control group (p = 0.001). ROC analysis was performed to find out ideal LV-GLS cut off value to predict the presence of CAT. A LV-GLS value of > - 17 has 81.3% sensitivity, 56.7% specificity to detect the presence of CAT. the present study is the first to focus on the assessing LV myocardial functions in patients with CAT by 3D-STE. CAT has a considerable negative effect on LV myocardial longitudinal deformation as evaluated by 3D strain parameters. Our results support that patients with CAT may have subclinical LV longitudinal deformation abnormalities even though they are apparently healthy.en_US
dc.identifier.doi10.1007/s10554-019-01760-0en_US
dc.identifier.endpage632en_US
dc.identifier.issn1569-5794
dc.identifier.issn1573-0743
dc.identifier.issue4en_US
dc.identifier.pmid31916067en_US
dc.identifier.scopus2-s2.0-85077630453en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage627en_US
dc.identifier.urihttps://doi.org/10.1007/s10554-019-01760-0
dc.identifier.urihttps://hdl.handle.net/11454/62540
dc.identifier.volume36en_US
dc.identifier.wosWOS:000523158700008en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Journal of Cardiovascular Imagingen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject3D-speckle tracking echocardiographyen_US
dc.subjectGlobal longitudinal strainen_US
dc.subjectCoronary artery tortuosityen_US
dc.subjectSubclinical left ventricular dysfunctionen_US
dc.titleCoronary tortuosity affects left ventricular myocardial functions: a 3D-speckle tracking echocardiography studyen_US
dc.typeArticleen_US

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