Endocrine assessment, chemotherapy, nonsurgical treatment, and rehabilitation for osteoporotic spine fractures: WFNS spine committee recommendations

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dc.authoridKim, Se-Hoon/0000-0002-1716-1375
dc.authorscopusid57200393472
dc.authorscopusid57901044300
dc.authorscopusid57901044400
dc.authorscopusid33968027300
dc.authorscopusid7004827180
dc.contributor.authorKim, Se-Hoon
dc.contributor.authorRamani, Prem S.
dc.contributor.authorJahagirdar, Vidhya R.
dc.contributor.authorRoitberg, Ben
dc.contributor.authorZileli, Mehmet
dc.date.accessioned2023-01-12T20:12:04Z
dc.date.available2023-01-12T20:12:04Z
dc.date.issued2022
dc.departmentN/A/Departmenten_US
dc.description.abstractINTRODUCTION: We reviewed the endocrine assessment, chemotherapy, and rehabilitation of the osteoporotic vertebral fractures (OVF) to create recommendations for the disease. EVIDENCE ACQUISITION: A PubMed and Medline search between 2011 and 2021 was conducted using key words. Case reports, experimental studies, papers other than the English language, and unrelated studies were excluded. Up to date information on endocrine assessment, medical and nonsurgical treatment, and rehabilitation for osteoporotic spine fractures were reviewed, and statements were produced to reach a consensus in two separate virtual consensus meetings of the World Federation of Neurosurgical Societies (WFNS) Spine Committee. The statements were voted and achieved a positive or negative consensus using Delphi method. EVIDENCE SYNTIIESIS: Endocrine assessment of osteoporosis is necessary if it is diagnosed in premenopausal women or men less than 50 years of age. Dual X-Ray absorptiometry (DXA) alone may not be predictive of fracture. Endocrine causes of osteoporosis must also be evaluated if the Z-score <=-2.0. In case of a vertebral fracture in postmenopausal women and men aged 50 years and above, pharmacologic treatment for osteoporosis must be started. Strengthening exercise, balance and gait training, and assistive devices are recommended to prevent and reduce falls in the elderly. In addition, rehabilitation must be a part of the overall treatment to help patients return to function. CONCLUSIONS: Nonsurgical management helps treat OVF. Although there is weak evidence on the type of medical treatment and usage of braces, bed rest, and other measures, current literature supports endocrinological management, medical treatment, and rehabilitation after osteoporotic vertebral fractures.en_US
dc.identifier.doi10.23736/S0390-5616.22.05641-7
dc.identifier.endpage310en_US
dc.identifier.issn0390-5616
dc.identifier.issn1827-1855
dc.identifier.issue4en_US
dc.identifier.pmid36153880en_US
dc.identifier.scopus2-s2.0-85138504774en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage300en_US
dc.identifier.urihttps://doi.org/10.23736/S0390-5616.22.05641-7
dc.identifier.urihttps://hdl.handle.net/11454/78242
dc.identifier.volume66en_US
dc.identifier.wosWOS:000891143000004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherEdizioni Minerva Medicaen_US
dc.relation.ispartofJournal of Neurosurgical Sciencesen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectOsteoporosisen_US
dc.subjectSpinal fracturesen_US
dc.subjectEndocrinologyen_US
dc.subjectBracesen_US
dc.subjectRehabilitationen_US
dc.subjectPostmenopausal Osteoporosisen_US
dc.subjectBack-Painen_US
dc.subjectManagementen_US
dc.subjectWomenen_US
dc.subjectVertebroplastyen_US
dc.subjectMetaanalysisen_US
dc.subjectSocietyen_US
dc.subjectFallsen_US
dc.subjectBoneen_US
dc.subjectKyphoplastyen_US
dc.titleEndocrine assessment, chemotherapy, nonsurgical treatment, and rehabilitation for osteoporotic spine fractures: WFNS spine committee recommendationsen_US
dc.typeReviewen_US

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