The predictive value of biochemical parameters in evaluating patients with abdominal trauma: The new scoring system

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dc.contributor.authorMusalar, Ekrem
dc.contributor.authorErsel, Murat
dc.contributor.authorAkarca, Funda Karbek
dc.contributor.authorKiyan, Guclu Selahattin
dc.contributor.authorCan, Ozge
dc.date.accessioned2019-10-27T11:21:12Z
dc.date.available2019-10-27T11:21:12Z
dc.date.issued2017
dc.departmentEge Üniversitesien_US
dc.description.abstractAim: The aim of this study was to investigate the contribution of non-invasively and rapidly obtained biochemical parameter results to the diagnosis and follow-up of intraabdominal injuries in multitrauma patients. Material and Methods: A total of 2604 multitrauma patients who were treated following their referral to our emergency department between January 2009 and January 2012 were retrospectively reviewed. A logistic regression analysis was used in the risk assessment. Results: Statistically significant associations between intraabdominal injury and certain biochemical variables measured at the time of the referral were determined. These variables were hemoglobin <= 9.99 g/dL [odds ratio (OR): 6.25, 95% CI: 2.86-13.52, p < 0.0001], serum alanine amino transferase (ALT) >= 100 IU/L (OR: 34.45, 95% CI: 21.76-54.54, p < 0.0001), and serum lipase >= 61 U/L (OR: 10.44, 95% CI: 6.56-16.49, p < 0.0001). The pretest probability score was determined for each patient by adding the scores that were obtained from each factor. ROC curve analysis was performed to determine the diagnostic value of the pretest probability score for detecting intra-abdominal injury (area = 0.88; p < 0.0001). Conclusion: The results of our study demonstrated that biochemical parameters may contribute to the diagnosis and follow-up of intraabdominal injuries in multitrauma patients. In particular, ALT, AST, CK and myoglobin were found to have higher ORs than low hemoglobin. After these parameters are tested in larger scale studies in conjunction with the gold standard multislice abdominal CT, they may be used for establishing scores to evaluate the severity of abdominal injuries. Copyright (C) 2016 The Emergency Medicine Association of Turkey. Production and hosting by Elsevier B.V. on behalf of the Owner. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).en_US
dc.identifier.doi10.1016/j.tjem.2016.11.005en_US
dc.identifier.endpage55en_US
dc.identifier.issn1304-7361
dc.identifier.issue2en_US
dc.identifier.pmid28616615en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage48en_US
dc.identifier.urihttps://doi.org/10.1016/j.tjem.2016.11.005
dc.identifier.urihttps://hdl.handle.net/11454/32906
dc.identifier.volume17en_US
dc.identifier.wosWOS:000406457100003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKare Publen_US
dc.relation.ispartofTurkish Journal of Emergency Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMultitraumaen_US
dc.subjectAbdominal traumaen_US
dc.subjectBiochemical parametersen_US
dc.subjectASTen_US
dc.subjectALTen_US
dc.subjectLipaseen_US
dc.subjectHemoglobinen_US
dc.titleThe predictive value of biochemical parameters in evaluating patients with abdominal trauma: The new scoring systemen_US
dc.typeArticleen_US

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