Soft tissue infection caused by Burkholderia cepacia in a child with polyarteritis nodosa

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dc.contributor.authorYildiz, Basak
dc.contributor.authorDuyu, Muhterem
dc.contributor.authorSozeri, Betul
dc.contributor.authorKarapinar, Bulent
dc.date.accessioned2019-10-27T21:40:57Z
dc.date.available2019-10-27T21:40:57Z
dc.date.issued2012
dc.departmentEge Üniversitesien_US
dc.description.abstractBurkholderia cepacia belongs to a family of Burkholderia species previously described as Pseudomonas cepacia, especially in patients suffering from cystic fibrosis. There are also many studies about this agent in the last decade due to their life-threatening infections and ability to invade mucosal and cellular surfaces. Here, we report a case of soft tissue infection caused by B. cepacia in a child with an underlying condition of polyarteritis nodosa. Her complaints started at two months of age and she was on cyclosporine therapy. She was treated several times because of soft tissue infections especially in her extremities. The most common causative agents were Pseudomonas spp. and Escherichia coli, but recently, another soft tissue infection accompanied by fever and signs of sepsis had developed. All blood, urine and tissue (debrided from the necrotic area) specimens were incubated. Empirical antibiotherapy with clindamycin was started and cyclosporine therapy was discontinued. B. cepacia was grown in the tissue specimen culture and was only susceptible to carbapenems. Meropenem therapy was administered throughout 14 days with a daily dosage of 60 mg/kg, and she was treated successfully at least in this attack of soft tissue infection, which caused more severe sepsis and tissue damage than the previous infections with other agents.en_US
dc.identifier.endpage666en_US
dc.identifier.issn0041-4301
dc.identifier.issue6en_US
dc.identifier.pmid23692797en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage664en_US
dc.identifier.urihttps://hdl.handle.net/11454/46467
dc.identifier.volume54en_US
dc.identifier.wosWOS:000209048700018en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish J Pediatricsen_US
dc.relation.ispartofTurkish Journal of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBurkholderia cepaciaen_US
dc.subjectdeep tissue infectionen_US
dc.subjectpolyarteritis nodosaen_US
dc.subjectantimicrobialsen_US
dc.titleSoft tissue infection caused by Burkholderia cepacia in a child with polyarteritis nodosaen_US
dc.typeArticleen_US

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