The infection risk of visceral leishmaniasis among household members of active patients

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dc.contributor.authorSakru, Nermin
dc.contributor.authorToz, Seray Ozensoy
dc.contributor.authorKorkmaz, Metin
dc.contributor.authorKavakli, Tulay
dc.contributor.authorAlkan, M. Ziya
dc.contributor.authorOzbel, Yusuf
dc.date.accessioned2019-10-27T19:18:29Z
dc.date.available2019-10-27T19:18:29Z
dc.date.issued2006
dc.departmentEge Üniversitesien_US
dc.description.abstractHuman visceral leishmaniasis (HVL), caused by Leishmania infantum is mainly observed as sporadic cases in Turkey and dogs are considered as the main reservoir of the disease. The incidence of visceral leishmaniasis among members of households where a HVL infection has already been diagnosed was studied in clusters around the diagnosed cases in different regions in Turkey. A total of 47 serum samples collected from the households of 11 proven visceral leishmaniasis patients were screened for anti-Leishmania antibodies by indirect immunofluorescent antibody test (IFAT). Three and one such household members belonging to the different families were found to be seropositive and borderline, respectively. Diagnosis was confirmed with the presence of amastigotes in bone marrow aspiration samples in all seropositives while the borderline case with slight and indefinitive symptoms of VL was followed only serologically at 3-month intervals and improved spontaneously in I year. Household members of individuals with previously confirmed visceral leishmaniasis were found to have higher frequency of the disease suggesting the household members should be included in the risk group for visceral leishmaniasis and serological screening should be performed for the detection of possible infection. (c) 2005 Elsevier Ireland Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.parint.2005.10.008en_US
dc.identifier.endpage133en_US
dc.identifier.issn1383-5769
dc.identifier.issue2en_US
dc.identifier.pmid16412686en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage131en_US
dc.identifier.urihttps://doi.org/10.1016/j.parint.2005.10.008
dc.identifier.urihttps://hdl.handle.net/11454/38598
dc.identifier.volume55en_US
dc.identifier.wosWOS:000237634100007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Ireland Ltden_US
dc.relation.ispartofParasitology Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectleishmaniasisen_US
dc.subjectdiagnosisen_US
dc.subjectIFATen_US
dc.subjecthousehold membersen_US
dc.subjectTurkeyen_US
dc.titleThe infection risk of visceral leishmaniasis among household members of active patientsen_US
dc.typeArticleen_US

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