Learning induces changes in the central cholinergic system of the rat in a sexually dimorphic pattern

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dc.contributor.authorPögün Ş.
dc.contributor.authorDemirgören S.
dc.contributor.authorKutay F.Z.
dc.contributor.authorOkur B.
dc.date.accessioned2019-10-27T09:02:19Z
dc.date.available2019-10-27T09:02:19Z
dc.date.issued1992
dc.departmentEge Üniversitesien_US
dc.description.abstractThe involvement of the central cholinergic system in learning and the possible sexual dimorphism in related brain responses were investigated. Rats were exposed to different environmental conditions and to active avoidance learning. The resulting changes were studied using the following approaches: muscarinic receptor binding (MRB), acetylcholinesterase (AChE) and choline acetyltransferase (CAT) activities. The statistical evaluation of the data reveal that learning induces changes, especially in the postsynaptic component of the central cholinergic system, which shows some sexual dimorphism, and that males and females respond with different levels of increased cholinergic activity to informal and associative learning. © 1992.en_US
dc.description.sponsorship1987/067en_US
dc.description.sponsorships studyw as supportedb y the Ege Univer-esearchF oundation Grant No: 1987/067. The authors thank Mrs. Hatice Arsoy for her excellenta ssistancein learningt rials. --en_US
dc.identifier.doi10.1016/0167-8760(92)90015-4en_US
dc.identifier.endpage23en_US
dc.identifier.issn0167-8760
dc.identifier.issue1en_US
dc.identifier.pmid1522028en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage17en_US
dc.identifier.urihttps://doi.org/10.1016/0167-8760(92)90015-4
dc.identifier.urihttps://hdl.handle.net/11454/28351
dc.identifier.volume13en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofInternational Journal of Psychophysiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcetylcholinesteraseen_US
dc.subjectActive avoidance learningen_US
dc.subjectCentral cholinergic systemen_US
dc.subjectCholine acetyl transferaseen_US
dc.subjectInformal learningen_US
dc.subjectMuscarinic receptor bindingen_US
dc.subjectSexual dimorphismen_US
dc.titleLearning induces changes in the central cholinergic system of the rat in a sexually dimorphic patternen_US
dc.typeArticleen_US

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