Aktif Polipoidal Koroidal Vaskülopatili Gözlerde Fundus Otofloresans Özellikleri
Küçük Resim Yok
Tarih
2016
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Dergi Başlığı
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Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Aktif polipoidal koroidal vaskülopatili (PKV) gözlerin karakteristik fundus otofloresans (FOF) özelliklerini tanımlamak amaçlanmıştır. Gereç ve Yöntem: Çalışmaya Ocak 2012 ve Kasım 2014 tarihleri arasında Ege Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, Retina Birimi'nde aktif PKV tanısı konulan 29 hastanın 35 gözü dahil edilmiştir. Tüm hastalarda fundus fotoğrafı, spektral domain optik koherens tomografi, FOF görüntüleme, floresein anjiyografi ve indosiyanin yeşili anjiyografiyi (İSYA) içeren tam oftalmolojik muayene yapılmıştır. İSYA ile aktif PKV tanısı konulan ve lezyon komponentleri belirlenen gözlerde bu lezyonlara uyan retina alanlarındaki FOF özellikleri tanımlanmıştır.Bulgular: Çalışma grubunu oluşturan 29 (15 erkek, 14 kadın) hastanın ortalama yaşları 64,6±7,5 yıl (54-82 yıl) olarak bulunmuştur. İSYA ile aktif PKV tanısı konulan 35 gözün 11'inde (%31,4) polipoid lezyonlar, 10'unda (%28,6) anormal dallanan vasküler ağ (ADVA), 14'ünde (%40) ise polipoid lezyonlar ve ADVA'nın birlikte bulunduğu saptanmıştır. Polipoid lezyonların (25) İSYA'daki lokalizasyonlarına uyan retina alanlarında 4 ayrı patern FOF görüntüsü tespit edilmiştir. Bunlar; %72 (18) konfluent hipootofloresans ve onu çevreleyen hiperfluoresan halka, %8 (iki) hiperotofloresans ve onu çevreleyen hipootofluoresan halka, %4 (bir) konfluent hipootofloresans ve %4 (bir) granüler hipootofloresans şeklinde olup üç (%12) gözde ise hemoraji nedeni ile bloke hipootofloresans izlenmiştir. Toplam 24 ADVA lezyonunun hepsinde (%100), İSYA'daki lezyon lokalizasyonuna uyan alanlarda granüler hipootofloresans şeklinde bir FOF paterni elde edilmiştir.Sonuç: PKV'nin tipik lezyonları olan polipoid lezyonlar ve ADVA, FOF görüntülemede karakteristik otofluoresans özelliklerine sahiptirler. Non invaziv, kısa çekim süreli ve tekrarlanabilir bir yöntem olan FOF görüntüleme aktif PKV tanısını destekleyen, güvenilir bir tanı yöntemi olarak kabul edilebilir
Objectives: To define characteristic fundus autofluorescence (FAF) findings in eyes with active polypoidal choroidal vasculopathy (PCV).Materials and Methods: Thirty-five eyes of 29 patients with active PCV who were diagnosed at Ege University Faculty of Medicine, Department of Ophthalmology, Retina Division between January 2012 and November 2014 were included in the study. All the patients underwent a complete ophthalmological examination including fundus photography, spectral-domain optical coherence tomography, fluorescein angiography, FAF photography, and indocyanine green angiography (ICGA). ICGA was used to diagnose active PCV and identify lesion components. FAF findings were described at the retinal site of the corresponding lesions identified and diagnosed using ICGA. Results: The mean age of the 29 study patients (15 men, 14 women) was 64.6±7.5 years (range, 54-82 years). ICGA revealed active PCV in 35 eyes, consisting of polypoid lesions in 11 eyes (31.4%), branching vascular networks (BVN) in 10 eyes (28.6%), and a combination of polypoid lesions and BVNs in 14 eyes (40%). On FAF images, 4 different patterns were detected at the corresponding retinal sites of 25 polypoid lesions detected by ICGA: confluent hypoautofluorescence with a hyperautofluorescent ring in 18 eyes (72%), hyperautofluorescence with hypoautofluorescent ring in 2 eyes (8%), confluent hypoautofluorescence in 1 eye (4%), and granular hypoautofluorescence in 1 eye (4%). The remaining 3 eyes (12%) demonstrated blocked hypoautofluorescence because of the excessive hemorrhaging in the macula. The FAF images showed the granular hypoautofluorescent FAF pattern in all 24 BVNs (100%) consistent with the location of the lesions on ICGA.Conclusion: The typical PCV lesions, polypoid lesions and BVNs had characteristic autofluorescent findings on FAF imaging. Noninvasive, quick, and repeatable FAF imaging can be considered a reliable and helpful diagnostic technique for the diagnosis of active PCV
Objectives: To define characteristic fundus autofluorescence (FAF) findings in eyes with active polypoidal choroidal vasculopathy (PCV).Materials and Methods: Thirty-five eyes of 29 patients with active PCV who were diagnosed at Ege University Faculty of Medicine, Department of Ophthalmology, Retina Division between January 2012 and November 2014 were included in the study. All the patients underwent a complete ophthalmological examination including fundus photography, spectral-domain optical coherence tomography, fluorescein angiography, FAF photography, and indocyanine green angiography (ICGA). ICGA was used to diagnose active PCV and identify lesion components. FAF findings were described at the retinal site of the corresponding lesions identified and diagnosed using ICGA. Results: The mean age of the 29 study patients (15 men, 14 women) was 64.6±7.5 years (range, 54-82 years). ICGA revealed active PCV in 35 eyes, consisting of polypoid lesions in 11 eyes (31.4%), branching vascular networks (BVN) in 10 eyes (28.6%), and a combination of polypoid lesions and BVNs in 14 eyes (40%). On FAF images, 4 different patterns were detected at the corresponding retinal sites of 25 polypoid lesions detected by ICGA: confluent hypoautofluorescence with a hyperautofluorescent ring in 18 eyes (72%), hyperautofluorescence with hypoautofluorescent ring in 2 eyes (8%), confluent hypoautofluorescence in 1 eye (4%), and granular hypoautofluorescence in 1 eye (4%). The remaining 3 eyes (12%) demonstrated blocked hypoautofluorescence because of the excessive hemorrhaging in the macula. The FAF images showed the granular hypoautofluorescent FAF pattern in all 24 BVNs (100%) consistent with the location of the lesions on ICGA.Conclusion: The typical PCV lesions, polypoid lesions and BVNs had characteristic autofluorescent findings on FAF imaging. Noninvasive, quick, and repeatable FAF imaging can be considered a reliable and helpful diagnostic technique for the diagnosis of active PCV
Açıklama
Anahtar Kelimeler
Göz Hastalıkları
Kaynak
Türk Oftalmoloji Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
46
Sayı
4
