Analyses of Plasmids Harbouring Quinolone Resistance Determinants in Enterobacteriaceae Members

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dc.contributor.authorErac, Bayri
dc.contributor.authorYilmaz, Fethiye Ferda
dc.contributor.authorOzturk, Ismail
dc.contributor.authorAydemir, Sabire Sohret
dc.contributor.authorHosgor-Limoncu, Mine
dc.date.accessioned2019-10-27T11:19:08Z
dc.date.available2019-10-27T11:19:08Z
dc.date.issued2017
dc.departmentEge Üniversitesien_US
dc.description.abstractThe aim of this study was to explore the plasmid characteristics of eight clinical Enterobacteriaceae strains containing extended broad spectrum beta-lactamases and plasmid-mediated quinolone resistance. Plasmids were transferred by conjugation or transformation and resistance determinants were investigated by PCR. We showed that at least one plasmid harbouring qnrB or qnrS determinant was transferred by conjugation in five isolates. QepA determinant was confirmed to be on a non-conjugative plasmid. We found at least one beta-lactamase gene in seven of the eight clinical isolates having plasmid-mediated quinolone resistance, which indicated that these two resistance determinants were mostly on the same conjugative plasmids.en_US
dc.description.sponsorshipEge University Scientific Research ProjectEge University [12ECZ012]en_US
dc.description.sponsorshipThis study was supported as an Ege University Scientific Research Project (12ECZ012). The authors would like to thank to Prof. George A. Jacoby, Prof. Kunikazu Yamane, Prof. Osman Birol Ozgumus and Prof. Hasan Nazik for kindly providing the positive control strains and plasmids. The authors would like to thank to Prof. Zeki Topcu, Assoc. Prof. Sevil Zencir, PhD Hasan Akbaba and Ege University Faculty of Pharmacy Pharmaceutical Sciences and Research Center (FABAL).en_US
dc.identifier.endpage532en_US
dc.identifier.issn1733-1331
dc.identifier.issue4en_US
dc.identifier.pmid29319519en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage529en_US
dc.identifier.urihttps://hdl.handle.net/11454/32701
dc.identifier.volume66en_US
dc.identifier.wosWOS:000419424400013en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPolskie Towarzystwo Mikrobiologow-Polish Society Of Microbiologistsen_US
dc.relation.ispartofPolish Journal of Microbiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectbeta-lactamaseen_US
dc.subjectESBL-producing Enterobacteriaceaeen_US
dc.subjectplasmid-mediated quinolone resistanceen_US
dc.titleAnalyses of Plasmids Harbouring Quinolone Resistance Determinants in Enterobacteriaceae Membersen_US
dc.typeArticleen_US

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