Synthesis and Characterization of Functionalized Se-MCM-41 a New Drug Carrier Mesopore Composite

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dc.contributor.authorRahman, M. M.
dc.contributor.authorAznan, M. A. B. M.
dc.contributor.authorYusof, A. M.
dc.contributor.authorAnsaryr, H.
dc.contributor.authorSiddiqi, M. J.
dc.contributor.authorYusan, S.
dc.date.accessioned2019-10-27T11:21:37Z
dc.date.available2019-10-27T11:21:37Z
dc.date.issued2017
dc.departmentEge Üniversitesien_US
dc.description.abstractVarious nanocomposite materials play a number of important roles in modern science and technology including pharmaceutical science. Among these materials, mesoporous materials cover a large number of applications in drug delivery system. The quantitative incorporation and high dispersion of selenium nanoparticles into MCM-41 have been made possible by the coordination between Se(IV) ion and aminopropyltriethoxysilane (APTES)-anchored MCM-41. The samples were characterized by X-ray powder diffraction, Fourier-transformed infrared spectroscopy (FTIR), scanning electron microscopy (SEM), nitrogen adsorption-desorption via multi-point Brunauer, Emmett and Teller (BET) analysis, Raman spectroscopy and UV-Vis diffusion reflection spectroscopy (UV-vis/DRS). The increase in cell parameter and the decrease in surface area observed by N-2 adsorption-desorption technique were taken as evidence of selenium introduction inside the MCM-41 framework. The behaviour of drug release in these nanocomposites is probably due to hydrogen bonding interactions between drug and the hydroxyl group on the composite framework.en_US
dc.description.sponsorshipResearch Management Center of UniversitiTeknologi Malaysia (UTM)en_US
dc.description.sponsorshipThe authors are profoundly grateful for the financial support given by the Research Management Center of UniversitiTeknologi Malaysia (UTM) during the tenure of this work conducted at the Department of Chemistry, Faculty of Science. Two of us, SY and RHA, also wish to thank EgeUniversitesi, Izmir, Turkey and Rajshahi University, Bangladesh respectively, for the leave granted to conduct this work at UTM and IIUM.en_US
dc.identifier.doi10.13005/ojc/330208
dc.identifier.endpage621en_US
dc.identifier.issn0970-020X
dc.identifier.issn2231-5039
dc.identifier.issn0970-020Xen_US
dc.identifier.issn2231-5039en_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage611en_US
dc.identifier.urihttps://doi.org/10.13005/ojc/330208
dc.identifier.urihttps://hdl.handle.net/11454/32933
dc.identifier.volume33en_US
dc.identifier.wosWOS:000404649200008en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherOriental Scientific Publ Coen_US
dc.relation.ispartofOriental Journal of Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMesoporous materialsen_US
dc.subjectMCM-41en_US
dc.subjectSe-MCM-41en_US
dc.titleSynthesis and Characterization of Functionalized Se-MCM-41 a New Drug Carrier Mesopore Compositeen_US
dc.typeArticleen_US

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