Synthesis and Characterization of Functionalized Se-MCM-41 a New Drug Carrier Mesopore Composite

Küçük Resim Yok

Tarih

2017

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Oriental Scientific Publ Co

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Various nanocomposite materials play a number of important roles in modern science and technology including pharmaceutical science. Among these materials, mesoporous materials cover a large number of applications in drug delivery system. The quantitative incorporation and high dispersion of selenium nanoparticles into MCM-41 have been made possible by the coordination between Se(IV) ion and aminopropyltriethoxysilane (APTES)-anchored MCM-41. The samples were characterized by X-ray powder diffraction, Fourier-transformed infrared spectroscopy (FTIR), scanning electron microscopy (SEM), nitrogen adsorption-desorption via multi-point Brunauer, Emmett and Teller (BET) analysis, Raman spectroscopy and UV-Vis diffusion reflection spectroscopy (UV-vis/DRS). The increase in cell parameter and the decrease in surface area observed by N-2 adsorption-desorption technique were taken as evidence of selenium introduction inside the MCM-41 framework. The behaviour of drug release in these nanocomposites is probably due to hydrogen bonding interactions between drug and the hydroxyl group on the composite framework.

Açıklama

Anahtar Kelimeler

Mesoporous materials, MCM-41, Se-MCM-41

Kaynak

Oriental Journal of Chemistry

WoS Q Değeri

N/A

Scopus Q Değeri

N/A

Cilt

33

Sayı

2

Künye