Radiological incomplete thymus involution in systemic sclerosis
Küçük Resim Yok
Tarih
2009
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Oxford Univ Press
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Methods. Sixty-three female SSc patients (diffuse/limited: 49/14), all having pulmonary high-resolution CT (HRCT) scans, taken previously for evaluating lung involvement were included. At the time of the scans, mean age and disease duration of the patients were 50.1 8.5 and 10.2 7.8 years, respectively. As the control group, 45 age-matched female patients, having normal pulmonary HRCT scans taken previously for evaluating non-specific symptoms, were included. Results. Frequency of incomplete thymus involution was significantly higher in SSc patients (12/63; 19) compared with the control group (2/45; 4.4; P 0.022). In SSc patients with pulmonary fibrosis, incomplete thymus involution was significantly lower (3/38; 7.9) than those without pulmonary fibrosis (9/25; 36; P 0.007). Conclusion. The present study shows significantly higher frequency of radiological incomplete thymus involution in SSc compared with normal controls. Furthermore, less common occurrence of pulmonary fibrosis in SSc patients with incomplete thymus involution deserves attention. These findings may have some implications regarding the possible role of thymic abnormalities at least in some patients with SSc.
Açıklama
Anahtar Kelimeler
Systemic sclerosis, Scleroderma, Thymus, Incomplete thymus involution
Kaynak
Rheumatology
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
48
Sayı
7
