Acoustic Radiation Force Impulse Elastography May Predict Acute Rejection in Kidney Transplantation

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dc.contributor.authorGokalp, Cenk
dc.contributor.authorOytun, Merve Guner
dc.contributor.authorGunay, Emrah
dc.contributor.authorTamsel, Sadik
dc.contributor.authorSen, Sait
dc.contributor.authorSezer, Taylan Ozgur
dc.contributor.authorToz, Huseyin
dc.date.accessioned2021-05-03T20:36:46Z
dc.date.available2021-05-03T20:36:46Z
dc.date.issued2020
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground. Allograft biopsy that is done as indicated by clinical and laboratory clues about graft rejection provides a definitive diagnosis. Noninvasive methods that may be useful for predicting or diagnosing rejection are important for early diagnosis of possible rejection. Purpose. The aim of this study is to investigate the relationship between changes in shear wave velocity (SWV) values and renal allograft kidney biopsy findings. Material and Methods. Thirty-four end-stage renal failure patients who underwent living donor renal transplantation between January 2015 and July 2015 were enrolled in this prospective cohort study. Implantation, sixth-month protocol, and biopsies that were performed with suspicion of acute rejection were evaluated with renal Doppler ultrasound and elastography findings of recipients' preimplantation donor ultrasonography findings. Results. Comparison of renal ultrasound and elastography findings of 2 groups revealed a significant elevation in the resistive index (0.81 vs 0.63, P = .005) and pulsatility index (2.08 vs 1.20, P = .008) values in the rejection group, and no significant difference in the SWV values between the 2 groups. Delta (Delta)-SWV was calculated using the difference between acute rejection values and preimplantation, implantation, and sixth-month values showed a positive correlation between acute rejection (Delta-sixth month, r = 0.498, P = .030), tubulitis (Delta-pretransplant, r = 0.509, P = .037), and inflammation (Delta-pretransplant, r = 0.657, P = .004) scores. However, there were no correlations between Delta-SWV values and glomerulitis and peritubular capillaritis score. Conclusion. Changes in SWV may predict acute rejection in kidney transplantation pa-tients if the reference measurements were done at a more stable time after the transplantation.en_US
dc.identifier.doi10.1016/j.transproceed.2020.02.174en_US
dc.identifier.endpage3102en_US
dc.identifier.issn0041-1345
dc.identifier.issn1873-2623
dc.identifier.issue10en_US
dc.identifier.pmid32507711en_US
dc.identifier.startpage3097en_US
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2020.02.174
dc.identifier.urihttps://hdl.handle.net/11454/70203
dc.identifier.volume52en_US
dc.identifier.wosWOS:000591375500036en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleAcoustic Radiation Force Impulse Elastography May Predict Acute Rejection in Kidney Transplantationen_US
dc.typeArticleen_US

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