Liver transplantation for acute liver failure due to toxic agent ingestion in children

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dc.contributor.authorAkman, Sezin Asik
dc.contributor.authorCakir, Murat
dc.contributor.authorBaran, Masallah
dc.contributor.authorArikan, Cigdem
dc.contributor.authorYuksekkaya, Hasan Ali
dc.contributor.authorTumgor, Gokhan
dc.contributor.authorSaz, Ulas Eylem
dc.contributor.authorZeytunlu, Murat
dc.contributor.authorKilic, Murat
dc.contributor.authorAydogdu, Sema
dc.date.accessioned2019-10-27T20:48:04Z
dc.date.available2019-10-27T20:48:04Z
dc.date.issued2009
dc.departmentEge Üniversitesien_US
dc.description.abstractALF is characterized by sudden onset, impaired liver function, jaundice and encephalopathy, without previous liver disease. We analyzed the patients who underwent LT due to toxic agent induced ALF to raise community awareness about preventing the toxic agent induced ALF. Five children (three boys, two girls) underwent LT due to toxic agent ingestion. Toxic agents were mushroom poisoning (n = 2), Datura stramonium (n = 1), yellow phosphorous (n = 1) and INH (n = 1). On admission, one patient had stage IV, two had stage III and two had stage II hepatic encephalopathy but worsened during the follow-up. One patient had renal failure, and three patients required mechanical ventilation. Three patients underwent LRLT and others from a DD. Post-operative complications were managed by supportive managements successfully, and overall all the patients are alive (100% survival) without any organ sequelae. Although outcome of these patients are excellent, ALF may be prevented in these cases by educating the public about consuming mushrooms and toxic effects of wild plants, prohibiting fireworks and serial liver enzyme measurements after initiating INH.en_US
dc.identifier.doi10.1111/j.1399-3046.2008.01119.xen_US
dc.identifier.endpage1040en_US
dc.identifier.issn1397-3142
dc.identifier.issn1399-3046
dc.identifier.issue8en_US
dc.identifier.pmid19210266en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1034en_US
dc.identifier.urihttps://doi.org/10.1111/j.1399-3046.2008.01119.x
dc.identifier.urihttps://hdl.handle.net/11454/42649
dc.identifier.volume13en_US
dc.identifier.wosWOS:000271811200015en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofPediatric Transplantationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectacute liver failureen_US
dc.subjecttoxic hepatitisen_US
dc.subjectliver transplantationen_US
dc.subjectchildrenen_US
dc.titleLiver transplantation for acute liver failure due to toxic agent ingestion in childrenen_US
dc.typeArticleen_US

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