Mortality-related factors in older adults with delirium: A prospective observational study

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dc.authorid0000-0002-5462-5044
dc.authorid0000-0002-4803-5419
dc.authorid0000-0003-1780-8391
dc.contributor.authorBoran, Yigitcan
dc.contributor.authorAltunc, Yusuf Ali
dc.contributor.authorYalcinli, Sercan
dc.date.accessioned2025-04-17T12:50:22Z
dc.date.available2025-04-17T12:50:22Z
dc.date.issued2024
dc.departmentEge Üniversitesi, Tıp Fakültesi, Dahili Bilimler Bölümü, Acil Tıp Ana Bilim Dalı
dc.description.abstractBackground: Delirium is a common and serious neuropsychiatric syndrome characterized by acute changes in attention, cognition, and consciousness. It is frequently encountered in various clinical settings, including critical care units and postoperative care, and is associated with significant morbidity and mortality. Understanding the factors contributing to delirium-related mortality is crucial for improving patient outcomes and healthcare practices. However, the factors associated with mortality in delirium have not been well-defined in the literature. Objectives: This study aimed to identify factors influencing 3-month mortality in older adults with delirium presenting to the emergency department (ED). Methods: The study was conducted prospectively and delirium was screened using the brief Confusion Assesment Method (bCAM). The primary outcome was 3-month mortality. Mann-Whitney U and Chi-square tests compared groups, Spearman correlation analyzed correlations, and multivariate logistic regression identified risk factors. Results: Among 243 patients, 29.6% experienced in-hospital mortality, and 56.4% had 3-month mortality. Factors associated with increased mortality risk included prior delirium history (3.32-fold increase, 95%CI: 1.51-7.30), active malignancy (3.49-fold increase, 95%CI: 1.61-7.56) and increased respiratory rate (1.18-fold increase, 95%CI: 1.08-1.29). An increase in mean arterial pressure (MAP) was associated with a 0.98-fold decrease in mortality risk (95%CI: 0.96-0.99), increase in body temperature was associated with a 0.48-fold decrease in mortality risk (95%CI:0.31-0.76). Conclusion: In delirious older adults at the ED, higher respiratory rate, lower MAP, lower body temperature, active malignancy and prior delirium history signal elevated mortality risk.
dc.identifier.citationBoran, Y., Altuncı, Y. A., & Yalçınlı, S. (2024). Mortality-related factors in older adults with delirium: A prospective observational study. Geriatric Nursing (New York), 60, 427-432.
dc.identifier.doi10.1016/j.gerinurse.2024.10.005
dc.identifier.endpage432
dc.identifier.issn01974572
dc.identifier.issueDec
dc.identifier.pmid39413553
dc.identifier.scopus2-s2.0-85206236339
dc.identifier.scopusqualityQ2
dc.identifier.startpage427
dc.identifier.urihttps://doi.org/10.1016/j.gerinurse.2024.10.005
dc.identifier.urihttps://hdl.handle.net/11454/117112
dc.identifier.volume60
dc.identifier.wosWOS:001340470200001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorBoran, Yigitcan
dc.institutionauthorAltunc, Yusuf Ali
dc.institutionauthorYalcinli, Sercan
dc.institutionauthorid0000-0002-5462-5044
dc.institutionauthorid0000-0002-4803-5419
dc.institutionauthorid0000-0003-1780-8391
dc.language.isoen
dc.publisherMosby Elsevier
dc.relation.ispartofGeriatric Nursing
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectDelirium
dc.subjectEmergency department
dc.subjectMortality
dc.subjectOlder adults
dc.titleMortality-related factors in older adults with delirium: A prospective observational study
dc.typeArticle

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