GC-MS Investigation and Acetylcholinesterase Inhibitory Activity of Galanthus rizehensis

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dc.contributor.authorSarikaya, Buket Bozkurt
dc.contributor.authorSomer, Nehir Unver
dc.contributor.authorKaya, Gulen Irem
dc.contributor.authorOnur, Mustafa Ali
dc.contributor.authorBastida, Jaume
dc.contributor.authorBerkov, Strahil
dc.date.accessioned2019-10-27T21:52:43Z
dc.date.available2019-10-27T21:52:43Z
dc.date.issued2013
dc.departmentEge Üniversitesien_US
dc.description.abstractGC-MS (gas chromatography-mass spectrometry) analyses of alkaloids in the aerial parts and bulbs of Galanthus rizehensis Stern (Amaryllidaceae), collected during two different vegetation periods, was performed. Twenty three alkaloids were identified in four different alkaloid extracts. Acetylcholinesterase (AChE) inhibitory activities of the alkaloid extracts were tested. Both the highest alkaloid diversity and the most potent inhibitory activity (IC50 12.94 mu g/ml) were obtained in extracts from the bulbs of G. rizehensis collected during the fruiting period.en_US
dc.description.sponsorshipTUBITAKTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [TBAG-104T272]; EBILTEMEge University [2007/BIL/007]; Ege University Research FundEge University [09/ECZ/014, 09/ECZ/021]; TUBITAK-BIDEBTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK)en_US
dc.description.sponsorshipThis study was financially supported by TUBITAK (TBAG-104T272), EBILTEM (2007/BIL/007), Ege University Research Fund (09/ECZ/014, 09/ECZ/021). B. B. S. thanks TUBITAK-BIDEB for a research fellowship. The authors also thank Dr. Asuncion Marin (Serveis Cientificotecnics, Universitat de Barcelona, Facultat de Farmacia, Barcelona, Spain) for performing the GC-MS analyses.en_US
dc.identifier.doi10.5560/ZNC.2013.68c0118en_US
dc.identifier.endpage124en_US
dc.identifier.issn0939-5075
dc.identifier.issn1865-7125
dc.identifier.issue03.Apren_US
dc.identifier.pmid23819307en_US
dc.identifier.startpage118en_US
dc.identifier.urihttps://doi.org/10.5560/ZNC.2013.68c0118
dc.identifier.urihttps://hdl.handle.net/11454/47717
dc.identifier.volume68en_US
dc.identifier.wosWOS:000322090700007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWalter De Gruyter Gmbhen_US
dc.relation.ispartofZeitschrift Fur Naturforschung Section C-A Journal of Biosciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGalanthus rizehensisen_US
dc.subjectAlkaloidsen_US
dc.subjectGC-MSen_US
dc.subjectAcetylcholinesterase Inhibitionen_US
dc.titleGC-MS Investigation and Acetylcholinesterase Inhibitory Activity of Galanthus rizehensisen_US
dc.typeArticleen_US

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