What kind of changes occurred in clinical characteristics of deceased kidney donor recipients after national allocation system in Turkey? A single-center retrospective analysis

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dc.contributor.authorSolak I.
dc.contributor.authorSezer T.O.
dc.contributor.authorToz H.
dc.contributor.authorTatar E.
dc.contributor.authorSozbilen M.
dc.contributor.authorFirat O.
dc.contributor.authorHoscoskun C.
dc.date.accessioned2019-10-26T21:46:54Z
dc.date.available2019-10-26T21:46:54Z
dc.date.issued2012
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective: Clinical characteristics of recipients of deceased donor renal transplantations were evaluated in the period before versus after implmentation of The National Allocation System (NAS). Patients and Methods: We evaluated retrospectively clinical profiles of the 42 after NAS (June 2008-December 2010) versus 42 consecutive deceased donor renal transplantation patients before NAS. Patient and graft survival rates were assessed using the Kaplan-Meier method; graft function was assessed based on creatinine clearance with the Cockcroft Gault equation. Patient and donor data were obtained from medical records. Results: Recipients were older in the pre-NAS group (39 ± 8 vs 33 ± 8 years, respectively; P =.001) and median duration of preoperative dialysis was longer in the post-NAS group (103 ± 61 months vs 50 ± 36 months, respectively; P =.000). The average number of human leukocyte antigen-mismatched antigens were pre-NAS 3.4 ± 1.0 versus post-NAS 3.9 ± 1.2 (P =.05). Considering the recipients serological status 9 were hepatitis C virus (HCV)(+) and 2 hepatitis B virus (HBV)(+) among the post-NAS versus no HBV(+) and only 1 HCV(+) patient pre-NAS. Kaplan-Meier analysis of graft survival rates showed 90% at 1 and 85% at 3 years pre-NAS. Similar to 95% at 1 and 86% at 3 years for the post-NAS group (P >.05). Likewise, patient survival rates for both groups at 1 and 3 years were 97%. The mean parameter of donor age, allograft loss, cold ischemia time, patient death, number of retransplantations, HBV(+) patients, and delayed graft function were similar between groups (P >.05). Discussion: After NAS the transplant recipients were older, had a longer duration of dialysis, greater number of HLA mismatched antigens and, more HCV(+). No differences were observed in short-term patient and graft survival rates. © 2012 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.transproceed.2012.05.030en_US
dc.identifier.endpage1600en_US
dc.identifier.issn0041-1345
dc.identifier.issue6en_US
dc.identifier.pmid22841223en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1598en_US
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2012.05.030
dc.identifier.urihttps://hdl.handle.net/11454/18581
dc.identifier.volume44en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleWhat kind of changes occurred in clinical characteristics of deceased kidney donor recipients after national allocation system in Turkey? A single-center retrospective analysisen_US
dc.typeConference Objecten_US

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