Influence of influenza vaccination on recurrent hospitalization in patients with heart failure

Basit Öğe Kaydı
dc.contributor.authorKaya, H.
dc.contributor.authorBeton, O.
dc.contributor.authorAcar, G.
dc.contributor.authorTemizhan, A.
dc.contributor.authorCavusoglu, Y.
dc.contributor.authorGuray, U.
dc.contributor.authorZoghi, M.
dc.contributor.authorUral, D.
dc.contributor.authorEkmekci, A.
dc.contributor.authorGungor, H.
dc.contributor.authorSari, I.
dc.contributor.authorOguz, D.
dc.contributor.authorYucel, H.
dc.contributor.authorZorlu, A.
dc.contributor.authorYilmaz, M. B.
dc.date.accessioned2019-10-27T11:08:27Z
dc.date.available2019-10-27T11:08:27Z
dc.date.issued2017
dc.departmentEge Üniversitesien_US
dc.description.abstractThe current study aimed to evaluate the influence of regular annual influenza vaccinations on cardiovascular (CV) death and heart failure-related hospitalizations (HFrH) in stable outpatients with heart failure with reduced ejection fraction. The Turkish research team-HF (TREAT-HF) is a network undertaking multicenter, observational cohort studies in HF. This study is a subgroup analysis of TREAT-HF outpatient cohorts who completed a questionnaire on influenza vaccination status and for whom follow-up data were available. A total of 656 patients with available follow-up data for CV death and HFrH including recurrent hospitalization were included in the study. Patients were classified into two groups: those who received regular influenza vaccination (40 %) and those who did not receive vaccination. During a mean follow-up of 15 +/- 6 months, 113 (18 %) patients had CV death and 471 (72 %) patients had at least one HFrH. The CV death rate was similar in both groups of patients (16 vs. 19 %, p = 0.37), whereas, HFrH and recurrent HFrH were significantly less frequently encountered in patients who received regular influenza vaccination than in those who did not receive vaccination (43 vs. 92 % and 16 vs. 66 %, p < 0.001, respectively). In a multivariate Cox proportional hazards model - in addition to a few clinical factors - vaccination status (HR = 0.30, 95 % CI = 0.17-0.51, p < 0.001) and graduation from university (HR = 0.35, 95 % CI = 0.17-0.72, p = 0.004) remained independently associated with the risk of recurrent HFrH. Regular influenza vaccination does not influence CV deaths; however, it decreases HFrH including recurrent episodes of HFrH in outpatients with heart failure with reduced ejection fraction.en_US
dc.identifier.doi10.1007/s00059-016-4460-2en_US
dc.identifier.endpage315en_US
dc.identifier.issn0340-9937
dc.identifier.issn1615-6692
dc.identifier.issue3en_US
dc.identifier.pmid27460050en_US
dc.identifier.startpage307en_US
dc.identifier.urihttps://doi.org/10.1007/s00059-016-4460-2
dc.identifier.urihttps://hdl.handle.net/11454/32170
dc.identifier.volume42en_US
dc.identifier.wosWOS:000400680200010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherUrban & Vogelen_US
dc.relation.ispartofHerzen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectInfluenzaen_US
dc.subjectVaccinationen_US
dc.subjectHeart failureen_US
dc.subjectHospitalizationen_US
dc.subjectOutpatientsen_US
dc.titleInfluence of influenza vaccination on recurrent hospitalization in patients with heart failureen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu