Sustained attention deficits in manic and euthymic patients with bipolar disorder

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dc.contributor.authorBora, Emre
dc.contributor.authorVahip, Simavi
dc.contributor.authorAkdeniz, Fisun
dc.date.accessioned2019-10-27T19:17:34Z
dc.date.available2019-10-27T19:17:34Z
dc.date.issued2006
dc.departmentEge Üniversitesien_US
dc.description.abstractSustained attention deficits are proposed to be both state and trait indicators of bipolar disorder. The nature of these deficits and their association with medication and symptoms is not clear yet. The aim of this study was to investigate the impairments in various components of sustained attention task in euthymic and manic patients and was to investigate the relationship between the deficits in the manic state and medication effects. The performances of 37 manic patients, 34 euthymic patients with bipolar disorder and 34 control subjects on eight scores from Conners' CPT II, reflecting three different dimensions of sustained attention were compared. Similar to some recent findings, euthymic patients had decreased target sensitivity (omission errors) and response time inconsistency. The increased false responding (commission errors), perseveration and vigilance deficits were prominent in the manic patients. These state dependent impairments could not be explained by the impact of medication. In contrast, the exacerbation of seemingly trait-related impairments in the manic state can be at least partly explained by the impact of pharmacological therapy. (c) 2006 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.pnpbp.2006.04.016en_US
dc.identifier.endpage1102en_US
dc.identifier.issn0278-5846
dc.identifier.issue6en_US
dc.identifier.pmid16740350en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage1097en_US
dc.identifier.urihttps://doi.org/10.1016/j.pnpbp.2006.04.016
dc.identifier.urihttps://hdl.handle.net/11454/38417
dc.identifier.volume30en_US
dc.identifier.wosWOS:000239008600016en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofProgress in Neuro-Psychopharmacology & Biological Psychiatryen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectbipolar disorderen_US
dc.subjecteuthymiaen_US
dc.subjectmaniaen_US
dc.subjectsustained attentionen_US
dc.titleSustained attention deficits in manic and euthymic patients with bipolar disorderen_US
dc.typeReview Articleen_US

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