The efficacy of complete blood count parameters in the diagnosis of tubal ectopic pregnancy

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dc.contributor.authorEskicioglu, Fatma
dc.contributor.authorOzdemir, Alper Tunga
dc.contributor.authorTuran, Guluzar Arzu
dc.contributor.authorGur, Esra Bahar
dc.contributor.authorKasap, Esin
dc.contributor.authorGenc, Mine
dc.date.accessioned2019-10-27T22:05:33Z
dc.date.available2019-10-27T22:05:33Z
dc.date.issued2014
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective: Ectopic pregnancy (EP) is the major cause of maternal morbidity and is responsible for maternal mortality in the first trimester In order to reduce undesirable results, it is necessary to find rapid and accurate, non-surgical diagnostic tests for EP The goal of the study was to investigate the differences in complete blood count parameters between tubal EPs and healthy pregnancies in be used in the diagnosis of ectopic pregnancy Study design: White blood cell (WBC), neutrophil, monocyte, lymphocyte, platelet (PLT) counts, mean PLT volume (MPV) and PLT distribution width (POW) levels in the complete blood count samples have been obtained from subjects with diagnosed tubal EP (n=78; study group) and women with healthy intrauterine gestations (n=79; control group). Statistical comparisons between groups were performed using the t test Results: POW levels were found to be significantly higher in the control group than EP (p<0.001). However no differences between the study and control groups with regard to PLT and MPV levels were observed. WBC levels were found to be significantly higher in the EP group as compared to controls (p<0.001). When leukocyte differentials were compared, monocyte counts in the EP group were significantly higher than in controls (p=0.005). No statistically significant differences in neutrophil and lymphocyte values were observed in either group. Conclusion: POW as an indicator of PLT activation is lower in tubal EP than intrauterine pregnancy so, possibly endometrial invasion in the intrauterine pregnancy needs more PLT activation. Monocyte counts are higher in tubal indicating that monocyte activation in the pathophysiology of EP could be effective in the formation of tubal motility and microenvironment regulation.en_US
dc.identifier.endpage827en_US
dc.identifier.issn0017-0011
dc.identifier.issue11en_US
dc.identifier.pmid25675798en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage823en_US
dc.identifier.urihttps://hdl.handle.net/11454/48497
dc.identifier.volume85en_US
dc.identifier.wosWOS:000346330600004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherStudio Ken_US
dc.relation.ispartofGinekologia Polskaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectectopic pregnancyen_US
dc.subjectmonocyteen_US
dc.subjectplatelet activationen_US
dc.subjectleukocyte counten_US
dc.titleThe efficacy of complete blood count parameters in the diagnosis of tubal ectopic pregnancyen_US
dc.typeArticleen_US

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