Panayiotopoulos syndrome and Gastaut syndrome are distinct entities in terms of neuropsychological findings

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dc.contributor.authorKalem, Sukriye Akca
dc.contributor.authorElmali, Ayse Deniz
dc.contributor.authorDemirbilek, Veysi
dc.contributor.authorOktem, Oget
dc.contributor.authorYapici, Zuhal
dc.contributor.authorSaltik, Sema
dc.contributor.authorBaykan, Betul
dc.date.accessioned2020-12-01T12:09:17Z
dc.date.available2020-12-01T12:09:17Z
dc.date.issued2019
dc.departmentEge Üniversitesien_US
dc.descriptionSaltik, Sema/0000-0002-6749-5795; Elmali, Ayse Deniz/0000-0001-6380-9550en_US
dc.description.abstractBackground: Although the courses of self-limited focal epilepsies of childhood are considered as benign, a handful of studies suggested that these children may suffer from cognitive problems. Implementing tailor-made educational strategies would aid these children to reach their full potentials. Therefore, it is crucial to understand and differentiate the complete neuropsychological and behavioral profiles of these rather common syndromes. We aimed to examine the distinct cognitive and behavioral profiles of the Panayiotopoulos syndrome (PS) and the Gastaut syndrome (GS), comparatively. Method: Twenty patients with PS, 20 patients with GS, and 20 healthy controls have been recruited. the testing protocol included Wechsler Intelligence Scale for Children-Revised, Conner's Continuous Performance Test, Verbal Fluency Test, Stroop Color and Word Test, Color Trails Test, Tower of London Test, Symbol Digit Modalities Test, California Verbal Learning Test-Children's Version, Rey Complex Figure Test, Benton Face Recognition Test, Benton Judgment of Line Orientation, Peabody Picture Vocabulary Test, Reading and Writing Test, Child Behavior Checklist, Conner's Parent Rating Scale-48, and Behavior Rating Inventory of Executive Function. Demographical, clinical, electrophysiological data, and imaging findings have also been evaluated. Results: With regard to intelligence, the patients with PS scored less in all scales compared to the healthy controls. However, only the performance IQ (intelligence quotient) scores differed significantly between the patient groups, with the patients with PS scoring lower than the patients with GS. Verbal memory problems were eminent in both of the patient groups; whereas, visual memory was impaired only in the group with PS. Psychomotor speed was affected in both groups. Reading problems were prominent only in the patients with PS. Writing and arithmetic skills were defective in both patient groups. There were no noteworthy behavioral problems in comparison to healthy subjects. Conclusion: Using neuropsychological profiles, this study demonstrated that the GS and the PS are two distinct entities. Cognitive dysfunction is a more prominent and widespread feature of the patients with PS; whereas, the patients with GS suffer only from milder and isolated cognitive problems. (c) 2019 Elsevier Inc. All rights reserved.en_US
dc.description.sponsorshipIstanbul University Scientific Research FundIstanbul University [2017-24851]en_US
dc.description.sponsorshipThis study was supported by the Istanbul University Scientific Research Fund with a project no. 2017-24851.en_US
dc.identifier.doi10.1016/j.yebeh.2019.106447en_US
dc.identifier.issn1525-5050
dc.identifier.issn1525-5069
dc.identifier.pmid31398558en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1016/j.yebeh.2019.106447
dc.identifier.urihttps://hdl.handle.net/11454/63392
dc.identifier.volume99en_US
dc.identifier.wosWOS:000580869300017en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAcademic Press Inc Elsevier Scienceen_US
dc.relation.ispartofEpilepsy & Behavioren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIdiopathic childhood occipital epilepsyen_US
dc.subjectOccipital epilepsyen_US
dc.subjectCognitionen_US
dc.subjectBehavioren_US
dc.subjectPanayiotopoulos syndromeen_US
dc.subjectGastaut syndromeen_US
dc.titlePanayiotopoulos syndrome and Gastaut syndrome are distinct entities in terms of neuropsychological findingsen_US
dc.typeArticleen_US

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