In-vitro fertilization outcome predictors in women with high baseline follicle-stimulating hormone levels: Analysis of over 1000 cycles from a tertiary center

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dc.contributor.authorSahin G.
dc.contributor.authorAkdogan A.
dc.contributor.authorAydın M.H.
dc.contributor.authorTekindal M.A.
dc.contributor.authorGöker E.N.T.
dc.contributor.authorTavmergen E.
dc.date.accessioned2021-05-03T20:59:01Z
dc.date.available2021-05-03T20:59:01Z
dc.date.issued2021
dc.description.abstractObjective: The present study aimed to evaluate reproductive outcomes and determine the predictors of clinical pregnancy and live birth in women with elevated baseline follicle-stimulating hormone (FSH) levels, who have undergone intracytoplasmic sperm injection (ICSI) treatment. Methods: This retrospective study included 1011 ICSI cycles of women with high baseline FSH levels (> 10 IU/L), from a tertiary university IVF center between 2010 and 2015. Logistic regression analysis was performed to evaluate the prognostic factors of clinical pregnancy and live birth. Results: Among the 1011 ICSI cycles, the clinical pregnancy and live birth rates per oocyte retrieval were 19.5% and 14.3%, respectively. The live birth rates were 21.1% and 1.7% in women aged ?30 years and those aged ?40 years, respectively. In addition, the live birth rate was 1.47-fold higher in women from whom >3 oocytes were retrieved, compared to those from whom ?3 oocytes were retrieved (p=0.047). Logistic regression analysis indicated that the age categories ?30y, 36-39y and ?40y, level of baseline FSH (?20 IU/L) and the ovarian response (?3 or >3 oocytes retrieved) were significantly associated with live birth. Conclusions: Our study indicated that age, baseline FSH level, and ovarian response are independent predictive factors for clinical pregnancy and live birth among women with baseline FSH levels >10 IU/L. © 2021, Sociedade Brasileira de Reproducao Assistida. All rights reserved.en_US
dc.identifier.doi10.5935/1518-0557.20200088en_US
dc.identifier.endpage241en_US
dc.identifier.issn1517-5693
dc.identifier.issue2en_US
dc.identifier.pmid33710840en_US
dc.identifier.scopus2-s2.0-85104182208en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage235en_US
dc.identifier.urihttps://doi.org/10.5935/1518-0557.20200088
dc.identifier.urihttps://hdl.handle.net/11454/71545
dc.identifier.volume25en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSociedade Brasileira de Reproducao Assistidaen_US
dc.relation.ispartofJornal Brasileiro de Reproducao Assistidaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAgingen_US
dc.subjectAssisted reproductive techniquesen_US
dc.subjectFollicle stimulating hormoneen_US
dc.subjectLive birthen_US
dc.subjectPregnancy rateen_US
dc.titleIn-vitro fertilization outcome predictors in women with high baseline follicle-stimulating hormone levels: Analysis of over 1000 cycles from a tertiary centeren_US
dc.typeArticleen_US

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