Effects of BFR training in serum NRG-1 and IL-6 in overweight postmenopausal women

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dc.contributor.authorRezaee, Zeinab
dc.contributor.authorJavaheri, Seyed Ali Akbar Hashemi
dc.contributor.authorRashidlamir, Amir
dc.contributor.authorOral, Onur
dc.contributor.authorStavropoulos, Evangelia
dc.date.accessioned2024-08-25T18:47:48Z
dc.date.available2024-08-25T18:47:48Z
dc.date.issued2022
dc.departmentEge Üniversitesien_US
dc.description.abstractIntroduction: Menopause is a noticeable period in women's life accompanied by some physiological and psychological changes leading to health conditions such as obesity, overweighing, cardiovascular, and other inflammatory diseases.Aim: Due to the importance of health cares in this period and the effectiveness of exercise training to attenuate the symptoms, we aimed to compare the effects of an emerging exercise tool by blood flow restriction in limbs on two public health-related cytokines, IL-6 (Interleukin-6) and NRG-1 (Neuregulin-1) in comparison with traditional training in overweight postmenopausal women.Materials-Methods: 30 overweight post-menopausal women were randomly assigned into BFR (Blood Flow Restriction), HI (High Intensity), LI (Low Intensity) groups (n=10) and performed eight weeks of concurrent training three days a week. Two lower body and two upper body exercises at 20%1RM (20% of one repetition Maximum) load for BFR and LI groups and at 80%1RM (80% of one repetition Maximum) load for HI group in addition to 20 minutes of aerobic training at the end. IL-6 and NRG-1 levels were measured before and after the eight weeks of training sessions.Results: Group differences in IL-6 levels were observed in BFR and HI groups (p=0.001 in both groups) but not in LI group (p=0.29). Differences between groups were significant between BFR and LI (p=0,00) and HI and LI (p=0.007) but not between BFR and HI (p=0.11). For NRG-1 levels, group differences were observed in all three groups (p=0.001), (p=0.003), (p=0.007) and the differences between groups for NRG-1 levels were significant between BFR and LI (p=0.001) and HI and LI (p=0.038) but not between BFR and HI (p=0.065).Conclusion: Low-intensity BFR training and high-intensity traditional resistance training are functioning similarly on the levels of IL-6 and NRG-1 in postmenopausal women and low-intensity training with BFR is more effective than low-intensity traditional training in this proposition.en_US
dc.identifier.endpage554en_US
dc.identifier.issn1791-1362
dc.identifier.issn2241-1666
dc.identifier.issue4en_US
dc.identifier.startpage541en_US
dc.identifier.urihttps://hdl.handle.net/11454/102046
dc.identifier.volume27en_US
dc.identifier.wosWOS:001004203600006en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherTzaneio General Hospitalen_US
dc.relation.ispartofScientific Chroniclesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240825_Gen_US
dc.subjectBFR trainingen_US
dc.subjectNerogulin-1en_US
dc.subjectNRG-1en_US
dc.subjectInterleukin-6en_US
dc.subjectIL-6en_US
dc.subjectpost-menopausal womenen_US
dc.subjectMenopauseen_US
dc.subjectInflammatory Markersen_US
dc.subjectPhysical-Activityen_US
dc.subjectExerciseen_US
dc.subjectNeuregulin-1en_US
dc.subjectMuscleen_US
dc.subjectMenopauseen_US
dc.subjectSystemen_US
dc.subjectHealthen_US
dc.subjectRolesen_US
dc.titleEffects of BFR training in serum NRG-1 and IL-6 in overweight postmenopausal womenen_US
dc.typeArticleen_US

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