Effects of BFR training in serum NRG-1 and IL-6 in overweight postmenopausal women
Küçük Resim Yok
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Tzaneio General Hospital
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Introduction: Menopause is a noticeable period in women's life accompanied by some physiological and psychological changes leading to health conditions such as obesity, overweighing, cardiovascular, and other inflammatory diseases.Aim: Due to the importance of health cares in this period and the effectiveness of exercise training to attenuate the symptoms, we aimed to compare the effects of an emerging exercise tool by blood flow restriction in limbs on two public health-related cytokines, IL-6 (Interleukin-6) and NRG-1 (Neuregulin-1) in comparison with traditional training in overweight postmenopausal women.Materials-Methods: 30 overweight post-menopausal women were randomly assigned into BFR (Blood Flow Restriction), HI (High Intensity), LI (Low Intensity) groups (n=10) and performed eight weeks of concurrent training three days a week. Two lower body and two upper body exercises at 20%1RM (20% of one repetition Maximum) load for BFR and LI groups and at 80%1RM (80% of one repetition Maximum) load for HI group in addition to 20 minutes of aerobic training at the end. IL-6 and NRG-1 levels were measured before and after the eight weeks of training sessions.Results: Group differences in IL-6 levels were observed in BFR and HI groups (p=0.001 in both groups) but not in LI group (p=0.29). Differences between groups were significant between BFR and LI (p=0,00) and HI and LI (p=0.007) but not between BFR and HI (p=0.11). For NRG-1 levels, group differences were observed in all three groups (p=0.001), (p=0.003), (p=0.007) and the differences between groups for NRG-1 levels were significant between BFR and LI (p=0.001) and HI and LI (p=0.038) but not between BFR and HI (p=0.065).Conclusion: Low-intensity BFR training and high-intensity traditional resistance training are functioning similarly on the levels of IL-6 and NRG-1 in postmenopausal women and low-intensity training with BFR is more effective than low-intensity traditional training in this proposition.
Açıklama
Anahtar Kelimeler
BFR training, Nerogulin-1, NRG-1, Interleukin-6, IL-6, post-menopausal women, Menopause, Inflammatory Markers, Physical-Activity, Exercise, Neuregulin-1, Muscle, Menopause, System, Health, Roles
Kaynak
Scientific Chronicles
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
27
Sayı
4
